Radafaxine

From WikiMD.org
Jump to navigation Jump to search

Radafaxine (pronunciation: rah-duh-fax-een) is a pharmaceutical drug that was developed by GlaxoSmithKline for the treatment of depression and fatigue. It is a norepinephrine-dopamine reuptake inhibitor (NDRI) and is chemically related to bupropion.

Etymology

The term "Radafaxine" is a coined name, with no specific etymology. It is a common practice in the pharmaceutical industry to create unique, easily pronounceable names for new drugs.

Pharmacology

Radafaxine acts by inhibiting the reuptake of the neurotransmitters norepinephrine and dopamine, thereby increasing their availability in the brain. This mechanism of action is similar to that of other NDRIs, such as bupropion.

Clinical Use

Radafaxine was investigated for use in the treatment of depression and fatigue, including fatigue associated with multiple sclerosis. However, development was discontinued in the late-stage clinical trials due to lack of efficacy.

Related Terms

External links

Esculaap.svg

This WikiMD dictionary article is a stub. You can help make it a full article.


Languages: - East Asian 中文, 日本, 한국어, South Asian हिन्दी, Urdu, বাংলা, తెలుగు, தமிழ், ಕನ್ನಡ,
Southeast Asian Indonesian, Vietnamese, Thai, မြန်မာဘာသာ, European español, Deutsch, français, русский, português do Brasil, Italian, polski