5-APB

5-APB2DACS.svg

Chemical compound

5-APB
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PubChem	44469342
DrugBank
ChemSpider	23259124
KEGG

5-APB (5-(2-aminopropyl)benzofuran) is a chemical compound that is structurally related to MDMA and benzofuran. It is a member of the benzofuran class of compounds and has been used in scientific research as well as recreationally.

Chemical Properties

5-APB is a benzofuran derivative with the IUPAC name 1-(1-benzofuran-5-yl)propan-2-amine. Its chemical formula is C₁₁H₁₃NO. The compound is known for its psychoactive effects, which are similar to those of MDMA.

Pharmacology

5-APB acts as a serotonin-norepinephrine-dopamine reuptake inhibitor (SNDRI) and a serotonin releasing agent (SRA). This means it increases the levels of serotonin, norepinephrine, and dopamine in the brain, leading to its euphoric and empathogenic effects. These properties make it similar to other entactogens like MDMA.

Effects

The effects of 5-APB are reported to be similar to those of MDMA, including feelings of euphoria, increased empathy, and enhanced sensory perception. However, it may also have some stimulant effects due to its action on dopamine and norepinephrine.

Legal Status

The legal status of 5-APB varies by country. In some jurisdictions, it is classified as a controlled substance, while in others it may be legal or unregulated. It is important to check local laws before possessing or using 5-APB.

Safety and Toxicity

There is limited information on the safety and toxicity of 5-APB. As with other research chemicals, the long-term effects are not well understood. Users should exercise caution and be aware of the potential risks.

See Also

• MDMA
• Benzofuran
• Serotonin-norepinephrine-dopamine reuptake inhibitor
• Serotonin releasing agent
• Entactogen

References

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