Benfluorex
Benfluorex
Benfluorex (pronounced ben-fluor-ex) is a pharmaceutical drug that was primarily used as an anti-diabetic and anti-hyperlipidemic agent. It was withdrawn from the market due to its association with cardiac fibrosis and pulmonary hypertension.
Etymology
The term "Benfluorex" is derived from the chemical structure of the drug, which is a derivative of fenfluramine, a serotonin releasing agent. The prefix "ben-" refers to the presence of a benzene ring in its structure.
Usage
Benfluorex was used for the treatment of hyperlipidemia (high levels of fats in the blood) and diabetes mellitus type 2. It was marketed under the trade name Mediator by the pharmaceutical company Servier.
Side Effects
The use of Benfluorex has been associated with serious side effects, including cardiac fibrosis and pulmonary hypertension. These side effects led to its withdrawal from the market in many countries.
Withdrawal from the Market
Benfluorex was withdrawn from the market in 2009 after studies showed an increased risk of valvular heart disease in patients taking the drug. The European Medicines Agency (EMA) recommended the withdrawal of the drug from the market in all European Union countries.
See Also
- Fenfluramine
- Pharmaceutical drug
- Diabetes mellitus type 2
- Hyperlipidemia
- Cardiac fibrosis
- Pulmonary hypertension
External links
- Medical encyclopedia article on Benfluorex
- Wikipedia's article - Benfluorex
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