Dimethoxyamphetamine

Dimethoxyamphetamine (DMA) is a series of lesser-known psychedelic drugs similar in structure to amphetamine and to the major psychedelic drugs DOB and DOI. They were first synthesized by Alexander Shulgin and reported in his book PiHKAL (Phenethylamines i Have Known And Loved). Little is known about their dangers or toxicity.

Chemistry

Dimethoxyamphetamine, or DMA, is a series of compounds which are derivatives of amphetamine. The DMA series has three possible compounds, differentiated by the position of the two methoxy groups. These are: 2,4-DMA, 2,5-DMA, and 3,4-DMA.

Pharmacology

The pharmacology of DMA is not well known. It is assumed to act as a 5-HT2A receptor agonist and produce its effects by binding to and activating the 5-HT2A receptors in the brain, but this has not been confirmed.

Effects

The effects of DMA are not well documented, as it is a relatively obscure compound with little history of human usage. Anecdotal reports suggest that its effects are similar to those of other psychedelic amphetamines, but may be more intense and longer lasting.

Legality

In the United States, DMA is classified as a Schedule I drug under the Controlled Substances Act. This means it is illegal to manufacture, buy, possess, or distribute without a license from the Drug Enforcement Administration (DEA).

See also

• Phenethylamine
• Psychedelic drug
• Amphetamine
• DOB
• DOI
• Alexander Shulgin
• PiHKAL

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  2,4-Dimethoxyamphetamine structure

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  2,5-Dimethoxyamphetamine structure

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  3,4-Dimethoxyamphetamine structure