Staphylococcal infection
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| Staphylococcal infection | |
|---|---|
| Synonyms | N/A |
| Pronounce | N/A |
| Specialty | N/A |
| Symptoms | Boils, abscesses, cellulitis, impetigo, sepsis |
| Complications | Toxic shock syndrome, septicemia, endocarditis, osteomyelitis |
| Onset | Rapid |
| Duration | Varies |
| Types | N/A |
| Causes | Staphylococcus bacteria |
| Risks | Immunocompromised, diabetes, skin injury, hospitalization |
| Diagnosis | Culture, blood test, imaging |
| Differential diagnosis | Streptococcal infection, MRSA, cellulitis |
| Prevention | Hand washing, wound care, hygiene |
| Treatment | Antibiotics, drainage of abscesses |
| Medication | Penicillin, cephalosporins, vancomycin |
| Prognosis | Generally good with treatment |
| Frequency | Common |
| Deaths | N/A |
Staphylococcal infection is a type of infection caused by the Staphylococcus bacteria. This genus of bacteria is known for its ability to cause a variety of diseases, ranging from minor skin infections to severe systemic illnesses. One hallmark of staphylococcal infection is the formation of abscesses.[1]
Staphylococcus: Overview and Types
Staphylococcus is a genus of Gram-positive, non-spore-forming bacteria that are usually present as clusters resembling a bunch of grapes, a feature that gives the group its name. Notable species include S. aureus, S. epidermidis, and S. saprophyticus. S. aureus is particularly virulent and is often implicated in more serious staphylococcal infections.[2]
Pathophysiology of Staphylococcal Infections
Staphylococci can colonize various parts of the human body, particularly the skin and mucous membranes. Infections occur when these bacteria enter the body, often through a break in the skin, and evade the immune system. The bacteria may produce toxins and enzymes that cause tissue damage and facilitate the formation of abscesses.[3]
Clinical Presentation
Clinical presentation varies with the type and location of the infection. Skin and soft tissue infections typically present with symptoms like redness, swelling, and pain, often accompanied by the formation of abscesses. Systemic infections can lead to severe illnesses such as septicemia, endocarditis, and pneumonia. Diagnosis of staphylococcal infections primarily involves clinical assessment, along with laboratory testing such as culture and gram stain of the suspected site of infection. Advanced techniques like polymerase chain reaction (PCR) and matrix-assisted laser desorption/ionization time-of-flight (MALDI-TOF) mass spectrometry may also be employed.[4] Treatment of staphylococcal infections often involves antibiotics, the choice of which depends on the sensitivity of the infecting strain. Staphylococcal species are notorious for their ability to develop antibiotic resistance, necessitating careful selection and use of antibiotics. For abscesses, surgical drainage is usually required.[5]
Prevention and Control
Prevention of staphylococcal infections includes maintaining good personal hygiene, proper wound care, and effective sterilization in healthcare settings. Contact precautions are also important in controlling the spread of the bacteria, especially in hospital environments.[6]
See also
References
- ↑ , Staphylococcus aureus Infections, The New England Journal of Medicine, 1998, Vol. 339(Issue: 8), pp. 520–532, DOI: 10.1056/NEJM199808203390806, PMID: 9709046,
- ↑ , Coagulase-negative staphylococci, Clinical Microbiology Reviews, 2014, Vol. 27(Issue: 4), pp. 870–926, DOI: 10.1128/CMR.00109-13, PMID: 25278577, PMC: 4187637,
- ↑ , Staphylococcus aureus Infections: Epidemiology, Pathophysiology, Clinical Manifestations, and Management, Clinical Microbiology Reviews, 2015, Vol. 28(Issue: 3), pp. 603–661, DOI: 10.1128/CMR.00134-14, PMID: 26016486, PMC: 4451395,
- ↑ , Methicillin-resistant Staphylococcus aureus associated with animals and its relevance to human health, Frontiers in Microbiology, 2012, Vol. 3, pp. 127, DOI: 10.3389/fmicb.2012.00127, PMID: 22514547, PMC: 3322010,
- ↑ , Microbiology of Skin and Soft Tissue Infections in the Age of Community-Acquired Methicillin-Resistant Staphylococcus aureus, Diagnostic Microbiology and Infectious Disease, 2015, Vol. 81(Issue: 3), pp. 186–190, DOI: 10.1016/j.diagmicrobio.2015.04.007, PMID: 25934167,
- ↑ , Principles and Practice of Infectious Diseases, Churchill Livingstone Elsevier, 2014, ISBN 9781455748013,
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* Firmicutes (low-G+C) Infectious diseases
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Contributors: Prab R. Tumpati, MD