Vibrio vulnificus

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Vibrio vulnificus

Vibrio vulnificus under a microscope

Vibrio vulnificus is a species of Gram-negative bacteria that is part of the Vibrionaceae family. It is a halophilic (salt-loving) bacterium that is commonly found in marine environments such as estuaries, brackish ponds, or coastal areas. V. vulnificus is known for causing severe illness in humans, particularly through the consumption of contaminated seafood or exposure of open wounds to contaminated water.

Characteristics

Vibrio vulnificus is a curved rod-shaped bacterium that is motile due to a single polar flagellum. It is a facultative anaerobe, meaning it can survive in both oxygen-rich and oxygen-poor environments. The bacterium thrives in warm temperatures, typically found in waters with temperatures above 20°C (68°F).

Pathogenicity

V. vulnificus is highly pathogenic and can cause gastroenteritis, wound infections, and septicemia. The bacterium is particularly dangerous for individuals with liver disease, immunocompromised conditions, or iron overload disorders.

Gastroenteritis

Consumption of raw or undercooked shellfish, especially oysters, can lead to gastroenteritis caused by V. vulnificus. Symptoms include diarrhea, vomiting, and abdominal pain.

Wound Infections

Exposure of open wounds to contaminated seawater can result in wound infections. These infections can rapidly progress to necrotizing fasciitis, a severe condition that requires immediate medical attention.

Septicemia

In susceptible individuals, V. vulnificus can enter the bloodstream, leading to septicemia. This condition is characterized by fever, chills, hypotension, and blistering skin lesions. It has a high mortality rate if not treated promptly.

Prevention and Treatment

Preventive measures include avoiding the consumption of raw or undercooked shellfish and protecting open wounds from exposure to seawater. Treatment of V. vulnificus infections typically involves the use of antibiotics such as doxycycline or ceftazidime. In severe cases, surgical intervention may be necessary to remove infected tissue.

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Contributors: Prab R. Tumpati, MD