Pitted keratolysis

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Pitted Keratolysis

Pitted keratolysis (pronounced: pɪtɪd kɛrəˈlaɪsɪs) is a bacterial skin infection that affects the soles of the feet and, less commonly, the palms of the hands. It is characterized by small, shallow, and pitted depressions in the skin's surface.

Etymology

The term "pitted keratolysis" is derived from the Latin words "pittus" meaning pit, "kerato" meaning horn (a reference to the keratin layer of the skin), and "lysis" meaning dissolution or destruction.

Symptoms

The primary symptom of pitted keratolysis is the appearance of small, pitted, crater-like depressions or pits in the skin. These pits are typically 1-3mm in diameter and are often associated with a foul odor. Other symptoms may include skin discoloration, itching, and pain.

Causes

Pitted keratolysis is caused by several types of bacteria, including Corynebacterium, Dermatophilus congolensis, Kytococcus sedentarius, and Actinomyces. These bacteria proliferate in warm, moist environments and produce enzymes that dissolve the keratin in the skin, leading to the formation of pits.

Treatment

Treatment for pitted keratolysis typically involves the use of topical antibiotics such as erythromycin or clindamycin. In severe cases, oral antibiotics may be prescribed. Good foot hygiene, including keeping the feet dry and changing socks regularly, can also help to manage symptoms and prevent recurrence.

Related Terms

  • Dermatology: The branch of medicine dealing with the skin and its diseases.
  • Keratin: A type of protein that makes up the outer layer of the skin.
  • Corynebacterium: A genus of bacteria that are Gram-positive, aerobic, nonmotile, and rod-shaped.
  • Actinomyces: A genus of bacteria that are Gram-positive, anaerobic, and rod-shaped.

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