Histoid leprosy

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Histoid Leprosy

Histoid leprosy (pronunciation: his-toyd lep-ruh-see) is a rare form of leprosy, a chronic infectious disease caused by Mycobacterium leprae.

Etymology

The term "histoid" is derived from the Greek word "histos" meaning tissue, and the suffix "-oid" meaning like or similar. The term "leprosy" comes from the Greek word "lepra", which means scaly.

Definition

Histoid leprosy is characterized by firm, raised, and often shiny nodules and plaques on the skin. These lesions are typically found on the face, buttocks, and extremities. The disease is often associated with resistance to dapsone, a drug commonly used in the treatment of leprosy.

Symptoms

The main symptoms of histoid leprosy include:

  • Firm, raised skin nodules and plaques
  • Loss of sensation in the affected areas
  • Muscle weakness
  • Eye problems, such as glaucoma and cataract

Diagnosis

Diagnosis of histoid leprosy is typically made through a combination of clinical examination, skin biopsy, and laboratory tests. The skin biopsy can reveal the presence of Mycobacterium leprae bacteria.

Treatment

Treatment for histoid leprosy typically involves a combination of antibiotics, including rifampicin, clofazimine, and dapsone. This combination is often referred to as multidrug therapy (MDT).

Related Terms

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