Tuberculosis cutis orificialis

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Tuberculosis cutis orificialis (pronunciation: tu-ber-kyu-lo-sis ku-tis or-i-fi-sha-lis) is a rare form of cutaneous tuberculosis, a skin infection caused by Mycobacterium tuberculosis.

Etymology

The term "Tuberculosis cutis orificialis" is derived from Latin. "Tuberculosis" comes from the Latin word tuberculum meaning a small swelling, "cutis" is Latin for skin, and "orificialis" refers to any opening or orifice in the body.

Overview

Tuberculosis cutis orificialis is a secondary skin infection that occurs in individuals with active tuberculosis. It is often associated with a high degree of bacteremia and is considered a sign of severe systemic disease. The infection typically affects the mucous membranes of the mouth and nose, as well as the skin surrounding body orifices.

Symptoms

The primary symptom of tuberculosis cutis orificialis is the presence of painful, slow-healing ulcers at body orifices. These ulcers are often accompanied by fever, weight loss, and general malaise.

Diagnosis

Diagnosis of tuberculosis cutis orificialis is typically made through a combination of clinical examination, histopathology, and bacterial culture. A positive tuberculin skin test or interferon-gamma release assay (IGRA) can also support the diagnosis.

Treatment

Treatment for tuberculosis cutis orificialis involves a lengthy course of antitubercular therapy. This typically includes a combination of drugs such as isoniazid, rifampin, pyrazinamide, and ethambutol.

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