Gram-negative toe web infection

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Gram-negative toe web infection
Synonyms
Pronounce N/A
Specialty Dermatology, Infectious disease
Symptoms Itching, maceration, foul odor
Complications Cellulitis, secondary infection
Onset
Duration
Types N/A
Causes Gram-negative bacteria
Risks Excessive sweating, poor hygiene, tight footwear
Diagnosis Clinical examination, bacterial culture
Differential diagnosis Tinea pedis, Erythrasma
Prevention Proper foot hygiene, wearing breathable footwear
Treatment Topical antibiotics, antifungal creams
Medication Gentamicin, Polymyxin B
Prognosis Good with treatment
Frequency
Deaths N/A


Gram-negative toe web infection is a type of bacterial infection that affects the interdigital spaces of the toes, particularly the webbing between the toes. This condition is caused by Gram-negative bacteria, which are characterized by their resistance to multiple antibiotics due to the unique structure of their cell walls. Gram-negative toe web infections are a common form of skin infection that can lead to discomfort, itching, and a foul odor.

Causes and Risk Factors

The primary cause of Gram-negative toe web infection is the proliferation of Gram-negative bacteria in the moist and warm environment of the toe webs. These bacteria can include species such as Pseudomonas aeruginosa, Escherichia coli, and Klebsiella among others. Factors that increase the risk of developing this infection include poor hygiene, wearing tight or non-breathable footwear, frequent exposure to wet environments, and pre-existing skin conditions such as athlete's foot (tinea pedis).

Symptoms

Symptoms of Gram-negative toe web infection include:

  • Redness and inflammation of the affected area
  • Itching or burning sensation
  • Foul odor
  • Discharge or pus from the affected area
  • Pain and discomfort
  • Skin breakdown and ulceration in severe cases

Diagnosis

Diagnosis of a Gram-negative toe web infection is typically made based on the clinical presentation and symptoms. A healthcare provider may also take a swab of the affected area for laboratory analysis to identify the specific type of bacteria causing the infection. This can help in selecting the most effective antibiotic for treatment.

Treatment

Treatment for Gram-negative toe web infection usually involves antibiotics that are effective against Gram-negative bacteria. The choice of antibiotic can depend on the specific bacteria identified and their antibiotic resistance patterns. Treatment may be topical, using antibiotic creams or ointments applied directly to the affected area, or systemic, using oral antibiotics for more severe infections. In addition to antibiotics, keeping the affected area clean and dry, and practicing good foot hygiene are important in treating and preventing this condition.

Prevention

Preventive measures for Gram-negative toe web infection include:

  • Maintaining good foot hygiene by washing feet regularly and drying them thoroughly, especially between the toes
  • Wearing breathable footwear and moisture-wicking socks to keep feet dry
  • Changing socks regularly, especially if feet become sweaty
  • Avoiding walking barefoot in communal wet areas such as showers, locker rooms, and swimming pools

See Also

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Contributors: Prab R. Tumpati, MD