Cepharanthine

INN
Drug class
Routes of administration
Pregnancy category
Bioavailability
Metabolism
Elimination half-life
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CAS Number
PubChem	10206
DrugBank
ChemSpider	9791
KEGG

Cepharanthine is an antiinflammatory and antineoplastic compound isolated from Stephania.<ref>,

 Cepharanthine, an Alkaloid from Stephania cepharantha Hayata, Inhibits the Inflammatory Response in the RAW264.7 Cell and Mouse Models, 
 Inflammation, 
 2013,
 Vol. 37(Issue: 1),
 pp. 235–46,
 DOI: 10.1007/s10753-013-9734-8,
 PMID: 24045962,</ref> Due to these modalities, it has been shown effective against HTLV in lab research. <ref>, 
 Synergistic inhibition of HTLV-1-infected cell proliferation by combination of cepharanthine and a tetramethylnaphthalene derivative, 
 Anticancer Res., 
 2012,
 Vol. 32,
 pp. 2639–45,
 
 PMID: 22753721,</ref> Additionally, it has successfully been used to treat a diverse range of medical conditions, including radiation-induced leukopenia, idiopathic thrombocytopenic purpura, alopecia areata, alopecia pityrodes, venomous snakebites, xerostomia, sarcoidosis, refractory anemia and various cancer-related conditions. No safety issues have been observed with CEP, and side effects are very rarely reported. <ref>, 
 Therapeutic potential of the biscoclaurine alkaloid, cepharanthine, for a range of clinical conditions, 
 Pharmacol Rep, 
 
 Vol. 63,
 pp. 337-47,
 
 PMID: 21602589,</ref>

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