Fenclozic acid

Fenclozic Acid

Fenclozic Acid (pronunciation: fen-clo-zic acid) is a nonsteroidal anti-inflammatory drug (NSAID) that was developed in the 1960s but was withdrawn from the market due to its hepatotoxic effects.

Etymology

The term "Fenclozic Acid" is derived from the chemical name 2-(2,4-dichlorophenyl)-2-[[furan-2-ylmethylene]amino]oxyacetic acid. The prefix "fen-" is derived from the furan ring structure, "-clo-" from the chlorine atoms, and "-zic acid" from the carboxylic acid functional group.

Pharmacology

Fenclozic Acid is a type of NSAID that was developed for its anti-inflammatory and analgesic properties. It works by inhibiting the enzyme cyclooxygenase (COX), which is involved in the production of prostaglandins, substances in the body that cause inflammation, pain, and fever.

Adverse Effects

The use of Fenclozic Acid has been associated with hepatotoxicity, or liver damage. This led to its withdrawal from the market.

Related Terms

• Nonsteroidal anti-inflammatory drug
• Cyclooxygenase
• Prostaglandins
• Hepatotoxicity

External links

• Medical encyclopedia article on Fenclozic acid
• Wikipedia's article - Fenclozic acid

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