Lornoxicam

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Lornoxicam

Lornoxicam (pronounced lor-nox-i-cam) is a non-steroidal anti-inflammatory drug (NSAID) of the oxicam class, used to relieve pain and inflammation in various medical conditions.

Etymology

The term "Lornoxicam" is derived from the chemical name 6-chloro-4-hydroxy-2-methyl-N-2-pyridinyl-2H-thieno[2,3-e]-1,2-thiazine-3-carboxamide 1,1-dioxide.

Usage

Lornoxicam is primarily used to treat pain and inflammation associated with osteoarthritis, rheumatoid arthritis, and ankylosing spondylitis. It is also used for postoperative pain management.

Mechanism of Action

Lornoxicam works by inhibiting the enzyme cyclooxygenase (COX), which is involved in the production of prostaglandins. Prostaglandins play a key role in the body's inflammatory response.

Side Effects

Common side effects of Lornoxicam include nausea, vomiting, diarrhea, abdominal pain, and dizziness. In rare cases, it can cause serious gastrointestinal complications such as peptic ulcers, bleeding, or perforation.

Contraindications

Lornoxicam should not be used by individuals with a history of hypersensitivity to oxicam derivatives or any other component of the formulation. It is also contraindicated in patients with active peptic ulcer disease, severe heart failure, or severe liver or kidney impairment.

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