Benorilate

Benorilate is an ester-linked codrug of aspirin and paracetamol. It is classified as a nonsteroidal anti-inflammatory drug (NSAID) and is used to relieve pain and reduce inflammation.

Pharmacology

Benorilate is metabolized in the body to release the two active drugs, aspirin and paracetamol. Aspirin works by inhibiting the production of prostaglandins, chemicals that promote inflammation, pain, and fever. Paracetamol, on the other hand, is believed to inhibit a specific enzyme in the brain and spinal cord (central nervous system), which helps to reduce pain and fever.

Uses

Benorilate is used to treat mild to moderate pain and inflammation. It is often used for conditions such as arthritis, rheumatism, and other musculoskeletal disorders. It can also be used to relieve pain and reduce fever in conditions such as flu or common cold.

Side Effects

Like all medicines, benorilate can cause side effects, although not everybody gets them. Some common side effects include nausea, vomiting, diarrhea, and stomach pain. In rare cases, it can cause serious side effects such as bleeding, ulcers, and allergic reactions.

Precautions

Before taking benorilate, patients should inform their doctor if they have a history of stomach ulcers, bleeding disorders, asthma, or allergies. It should be used with caution in patients with liver or kidney disease. It is not recommended for use during pregnancy or breastfeeding without medical advice.

Interactions

Benorilate can interact with other medicines, including other NSAIDs, blood thinners, and certain antidepressants. It can also interact with alcohol, which can increase the risk of stomach bleeding.

See Also

• Aspirin
• Paracetamol
• Nonsteroidal anti-inflammatory drug
• Codrug

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