Flurbiprofen
A nonsteroidal anti-inflammatory drug
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Overview
Flurbiprofen is a nonsteroidal anti-inflammatory drug (NSAID) used to treat pain and inflammation. It is commonly prescribed for conditions such as arthritis, dental pain, and postoperative pain. Flurbiprofen works by inhibiting the production of prostaglandins, which are chemicals in the body responsible for inflammation and pain.
Pharmacology
Flurbiprofen is a member of the propionic acid class of NSAIDs, which also includes drugs like ibuprofen and naproxen. It is available in both oral and topical formulations. The drug is absorbed in the gastrointestinal tract and is metabolized in the liver. Its mechanism of action involves the inhibition of the cyclooxygenase (COX) enzymes, specifically COX-1 and COX-2, which are involved in the synthesis of prostaglandins.
Medical Uses
Flurbiprofen is used to manage various types of pain and inflammation. It is effective in treating:
- Osteoarthritis and rheumatoid arthritis
- Ankylosing spondylitis
- Dysmenorrhea (painful menstruation)
- Migraine
- Postoperative pain
Side Effects
Common side effects of flurbiprofen include:
Serious side effects may include:
Contraindications
Flurbiprofen should not be used in individuals with:
Interactions
Flurbiprofen may interact with other medications, including:
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