Salsalate

Salsalate is a nonsteroidal anti-inflammatory drug (NSAID) in the same class as aspirin. It is used to treat pain and inflammation caused by conditions such as rheumatoid arthritis, osteoarthritis, and related conditions.

Pharmacology

Salsalate is a prodrug, meaning it is metabolized in the body to produce the active drug. It is broken down in the body to salicylic acid, which is a known NSAID. Salicylic acid works by inhibiting the production of prostaglandins, which are chemicals that cause inflammation and pain in the body.

Uses

Salsalate is used to treat pain and inflammation caused by conditions such as rheumatoid arthritis, osteoarthritis, and related conditions. It can also be used to reduce fever and relieve minor aches and pains.

Side Effects

Like all NSAIDs, salsalate can cause side effects. These can include stomach upset, heartburn, nausea, vomiting, and diarrhea. More serious side effects can include stomach bleeding, kidney problems, and an increased risk of heart attack or stroke.

Interactions

Salsalate can interact with other medications, including blood thinners, other NSAIDs, and certain types of antidepressants. It is important to tell your doctor about all the medications you are taking before starting salsalate.

See Also

• Nonsteroidal anti-inflammatory drug
• Aspirin
• Rheumatoid arthritis
• Osteoarthritis

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