Tarenflurbil

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Tarenflurbil

Tarenflurbil (pronounced: tahr-en-flur-bil), also known as Flurizan, is a nonsteroidal anti-inflammatory drug (NSAID) that was investigated for its potential use in the treatment of Alzheimer's disease.

Etymology

The name "Tarenflurbil" is a combination of parts of the chemical name for the drug, which is 2-phenylmethylamino]-5-trifluoromethylphenyl]pentanoic acid.

Usage

Tarenflurbil was developed by Myriad Genetics, a biotechnology company based in the United States. It was designed to reduce the production of amyloid beta peptides, which are believed to be a primary cause of the neurodegeneration seen in Alzheimer's disease. However, in Phase III clinical trials, Tarenflurbil failed to show a significant effect on the progression of Alzheimer's disease, leading to the discontinuation of its development.

Related Terms

  • Nonsteroidal anti-inflammatory drug: A class of drugs that provides analgesic and antipyretic effects, and, in higher doses, anti-inflammatory effects.
  • Alzheimer's disease: A progressive disease that destroys memory and other important mental functions.
  • Amyloid beta: Peptides of 36–43 amino acids that are crucially involved in Alzheimer's disease as the main component of the amyloid plaques found in the brains of Alzheimer patients.
  • Myriad Genetics: A publicly traded American molecular diagnostic company based in Salt Lake City, Utah, United States.

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