Dexibuprofen
Dexibuprofen is a nonsteroidal anti-inflammatory drug (NSAID) used for its analgesic, anti-inflammatory, and antipyretic properties. It is the dextral or right-handed enantiomer of ibuprofen, which means it is one of the two mirror-image forms of the molecule. Dexibuprofen is considered to be more potent and to have fewer side effects compared to racemic ibuprofen, which contains both the dextrorotatory and levorotatory enantiomers.
Pharmacology
Dexibuprofen works by inhibiting the cyclooxygenase (COX) enzymes, specifically COX-1 and COX-2. These enzymes are involved in the synthesis of prostaglandins, which are mediators of inflammation, pain, and fever. By reducing the production of prostaglandins, dexibuprofen helps to alleviate symptoms associated with inflammatory conditions.
Medical Uses
Dexibuprofen is commonly prescribed for the treatment of various conditions, including:
Dosage and Administration
The dosage of dexibuprofen varies depending on the condition being treated and the patient's response to the medication. It is typically administered orally in the form of tablets. The usual dose ranges from 400 mg to 1200 mg per day, divided into multiple doses.
Side Effects
Common side effects of dexibuprofen include:
Serious side effects, although rare, may include:
Contraindications
Dexibuprofen should not be used in patients with:
- Hypersensitivity to ibuprofen or other NSAIDs
- Active peptic ulcer disease
- Severe heart failure
- Severe liver or kidney impairment
Interactions
Dexibuprofen may interact with other medications, including:
See Also
References
External Links
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