Zomepirac
Zomepirac
Zomepirac (pronunciation: zo-MEP-i-rak) is a nonsteroidal anti-inflammatory drug (NSAID) that was previously used for the management of mild to moderate pain.
Etymology
The term "Zomepirac" is derived from the chemical name of the drug, which is 4-(5,6,7,8-tetrahydro-3(2H)-pyrido[4,3-e]-1,2,4-thiadiazinyl)benzoic acid.
Usage
Zomepirac was primarily used as an analgesic for the relief of mild to moderate pain. It was also used as an anti-inflammatory agent in the treatment of rheumatoid arthritis and osteoarthritis.
Pharmacology
Zomepirac works by inhibiting the enzyme cyclooxygenase (COX), which is involved in the production of prostaglandins. Prostaglandins play a key role in the body's inflammatory response.
Side Effects
Common side effects of Zomepirac include gastrointestinal issues such as nausea, vomiting, and diarrhea. Serious side effects can include ulcers, bleeding, and perforation of the stomach or intestines.
Withdrawal from Market
Zomepirac was withdrawn from the market in 1983 due to the risk of serious allergic reactions, including anaphylaxis and severe hypotension (low blood pressure).
Related Terms
- Nonsteroidal anti-inflammatory drug
- Analgesic
- Rheumatoid arthritis
- Osteoarthritis
- Cyclooxygenase
- Prostaglandins
- Anaphylaxis
- Hypotension
External links
- Medical encyclopedia article on Zomepirac
- Wikipedia's article - Zomepirac
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