Zomepirac

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Zomepirac

Zomepirac (pronunciation: zo-MEP-i-rak) is a nonsteroidal anti-inflammatory drug (NSAID) that was previously used for the management of mild to moderate pain.

Etymology

The term "Zomepirac" is derived from the chemical name of the drug, which is 4-(5,6,7,8-tetrahydro-3(2H)-pyrido[4,3-e]-1,2,4-thiadiazinyl)benzoic acid.

Usage

Zomepirac was primarily used as an analgesic for the relief of mild to moderate pain. It was also used as an anti-inflammatory agent in the treatment of rheumatoid arthritis and osteoarthritis.

Pharmacology

Zomepirac works by inhibiting the enzyme cyclooxygenase (COX), which is involved in the production of prostaglandins. Prostaglandins play a key role in the body's inflammatory response.

Side Effects

Common side effects of Zomepirac include gastrointestinal issues such as nausea, vomiting, and diarrhea. Serious side effects can include ulcers, bleeding, and perforation of the stomach or intestines.

Withdrawal from Market

Zomepirac was withdrawn from the market in 1983 due to the risk of serious allergic reactions, including anaphylaxis and severe hypotension (low blood pressure).

Related Terms

External links

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