Basal-cell carcinoma: Difference between revisions
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[[File:Basal cell carcinoma.jpg|thumb|Photograph showing a typical basal-cell carcinoma]] | {{SI}} | ||
[[image:Basalioma.jpg|Basalioma|thumb]] | {{Infobox medical condition | ||
| name = Basal-cell carcinoma | |||
| image = [[File:Superficial_basal_cell_carcinoma.jpg|alt=Superficial basal cell carcinoma]] | |||
| caption = Superficial basal cell carcinoma | |||
| field = [[Dermatology]] | |||
| synonyms = Basal-cell cancer, basal cell epithelioma | |||
| symptoms = [[Skin lesion]] that may appear as a shiny bump, a reddish patch, or a sore that does not heal | |||
| complications = Rarely [[metastasis|metastasizes]], but can cause significant local destruction | |||
| onset = Most commonly in [[adulthood]] | |||
| duration = [[Chronic (medicine)|Chronic]] | |||
| causes = [[Ultraviolet]] light exposure, [[genetic predisposition]] | |||
| risks = [[Sun exposure]], [[fair skin]], [[radiation therapy]], [[immunosuppression]] | |||
| diagnosis = [[Skin biopsy]] | |||
| differential = [[Squamous-cell carcinoma]], [[melanoma]], [[sebaceous carcinoma]] | |||
| prevention = [[Sun protection]], avoiding [[tanning beds]] | |||
| treatment = [[Surgical excision]], [[Mohs surgery]], [[cryosurgery]], [[topical chemotherapy]] | |||
| prognosis = Excellent with treatment, but can recur | |||
| frequency = Most common form of [[skin cancer]] | |||
}} | |||
[[File:Basal cell carcinoma.jpg|left|thumb|Photograph showing a typical basal-cell carcinoma]] | |||
[[image:Basalioma.jpg|Basalioma|left|thumb]] | |||
'''Basal-cell carcinoma''' (BCC), also known as '''basal-cell cancer''', is the most common type of [[skin cancer]]. It often appears as a painless raised area of skin, which may be shiny with small [[blood vessel|blood vessels]] running over it. It may also present as a raised area with ulceration.<ref>{{Cite web|url=https://www.cancer.org/cancer/basal-and-squamous-cell-skin-cancer/about/what-is-basal-and-squamous-cell.html|title=What Is Basal and Squamous Cell Skin Cancer?|website=American Cancer Society|access-date=2023-05-04}}</ref> BCC grows slowly and can damage the tissue around it, but it is unlikely to spread to distant areas or result in death. | '''Basal-cell carcinoma''' (BCC), also known as '''basal-cell cancer''', is the most common type of [[skin cancer]]. It often appears as a painless raised area of skin, which may be shiny with small [[blood vessel|blood vessels]] running over it. It may also present as a raised area with ulceration.<ref>{{Cite web|url=https://www.cancer.org/cancer/basal-and-squamous-cell-skin-cancer/about/what-is-basal-and-squamous-cell.html|title=What Is Basal and Squamous Cell Skin Cancer?|website=American Cancer Society|access-date=2023-05-04}}</ref> BCC grows slowly and can damage the tissue around it, but it is unlikely to spread to distant areas or result in death. | ||
== Causes and Risk Factors == | == Causes and Risk Factors == | ||
Basal-cell carcinoma is primarily caused by overexposure to ultraviolet (UV) radiation from sunlight or artificial sources, such as tanning beds. Other risk factors include having light-colored or freckled skin, a personal or family history of BCC, chronic skin inflammation or injury, exposure to radiation or arsenic, and immunosuppression.<ref>{{Cite web|url=https://www.mayoclinic.org/diseases-conditions/basal-cell-carcinoma/symptoms-causes/syc-20354187|title=Basal cell carcinoma|website=Mayo Clinic|access-date=2023-05-04}}</ref> | Basal-cell carcinoma is primarily caused by overexposure to ultraviolet (UV) radiation from sunlight or artificial sources, such as tanning beds. Other risk factors include having light-colored or freckled skin, a personal or family history of BCC, chronic skin inflammation or injury, exposure to radiation or arsenic, and immunosuppression.<ref>{{Cite web|url=https://www.mayoclinic.org/diseases-conditions/basal-cell-carcinoma/symptoms-causes/syc-20354187|title=Basal cell carcinoma|website=Mayo Clinic|access-date=2023-05-04}}</ref> | ||
== Diagnosis == | == Diagnosis == | ||
Diagnosis of BCC often involves a skin examination, followed by a skin biopsy if a lesion is suspected to be cancerous.<ref>{{Cite web|url=https://www.cancer.org/cancer/basal-and-squamous-cell-skin-cancer/detection-diagnosis-staging/how-diagnosed.html|title=How Is Basal and Squamous Cell Skin Cancer Diagnosed?|website=American Cancer Society|access-date=2023-05-04}}</ref> | Diagnosis of BCC often involves a skin examination, followed by a skin biopsy if a lesion is suspected to be cancerous.<ref>{{Cite web|url=https://www.cancer.org/cancer/basal-and-squamous-cell-skin-cancer/detection-diagnosis-staging/how-diagnosed.html|title=How Is Basal and Squamous Cell Skin Cancer Diagnosed?|website=American Cancer Society|access-date=2023-05-04}}</ref> | ||
== Treatment == | == Treatment == | ||
Treatment options depend on the size, location, and number of lesions. They may include [[Mohs surgery]], simple excision, curettage and desiccation, cryotherapy, radiation therapy, topical medications, or in some cases, oral medications such as hedgehog pathway inhibitors.<ref>{{Cite web|url=https://www.mayoclinic.org/diseases-conditions/basal-cell-carcinoma/diagnosis-treatment/drc-20354190|title=Basal cell carcinoma - Diagnosis and treatment|website=Mayo Clinic|access-date=2023-05-04}}</ref> | Treatment options depend on the size, location, and number of lesions. They may include [[Mohs surgery]], simple excision, curettage and desiccation, cryotherapy, radiation therapy, topical medications, or in some cases, oral medications such as hedgehog pathway inhibitors.<ref>{{Cite web|url=https://www.mayoclinic.org/diseases-conditions/basal-cell-carcinoma/diagnosis-treatment/drc-20354190|title=Basal cell carcinoma - Diagnosis and treatment|website=Mayo Clinic|access-date=2023-05-04}}</ref> | ||
== Prognosis == | == Prognosis == | ||
While BCC is slow-growing and rarely metastasizes, it can cause significant cosmetic damage and functional impairment, especially when located near the eyes, ears, or nose. Early detection and treatment can reduce the risk of recurrence and prevent complications.<ref>{{Cite web|url=https://www.aad.org/public/diseases/skin-cancer/types/common/bcc/treatment|title=Basal cell carcinoma: Diagnosis and treatment|website=American Academy of Dermatology Association|access-date=2023-05-04}}</ref> | While BCC is slow-growing and rarely metastasizes, it can cause significant cosmetic damage and functional impairment, especially when located near the eyes, ears, or nose. Early detection and treatment can reduce the risk of recurrence and prevent complications.<ref>{{Cite web|url=https://www.aad.org/public/diseases/skin-cancer/types/common/bcc/treatment|title=Basal cell carcinoma: Diagnosis and treatment|website=American Academy of Dermatology Association|access-date=2023-05-04}}</ref> | ||
== Prevention == | == Prevention == | ||
Prevention strategies include reducing sun exposure, using sunscreen, and avoiding tanning beds. Regular skin self-examinations can also help detect this cancer at an early stage.<ref>{{Cite web|url=https://www.cdc.gov/cancer/skin/basic_info/prevention.htm|title=Prevention Tips|website=Centers for Disease Control and Prevention|access-date=2023-05-04}}</ref> | Prevention strategies include reducing sun exposure, using sunscreen, and avoiding tanning beds. Regular skin self-examinations can also help detect this cancer at an early stage.<ref>{{Cite web|url=https://www.cdc.gov/cancer/skin/basic_info/prevention.htm|title=Prevention Tips|website=Centers for Disease Control and Prevention|access-date=2023-05-04}}</ref> | ||
== See Also == | == See Also == | ||
* [[Skin cancer]] | * [[Skin cancer]] | ||
* [[Squamous-cell skin carcinoma]] | * [[Squamous-cell skin carcinoma]] | ||
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== References == | == References == | ||
{{reflist}} | {{reflist}} | ||
== External Links == | == External Links == | ||
* [https://www.cancer.org/cancer/basal-and-squamous-cell-skin-cancer.html Basal and Squamous Cell Skin Cancer - American Cancer Society] | * [https://www.cancer.org/cancer/basal-and-squamous-cell-skin-cancer.html Basal and Squamous Cell Skin Cancer - American Cancer Society] | ||
* [https://www.cancer.net/cancer-types/skin-cancer-non-melanoma Skin Cancer (Non-Melanoma) - Cancer.Net] | * [https://www.cancer.net/cancer-types/skin-cancer-non-melanoma Skin Cancer (Non-Melanoma) - Cancer.Net] | ||
* [https://www.aad.org/public/diseases/skin-cancer/types/common/bcc Basal Cell Carcinoma - American Academy of Dermatology Association] | * [https://www.aad.org/public/diseases/skin-cancer/types/common/bcc Basal Cell Carcinoma - American Academy of Dermatology Association] | ||
== Further Reading == | == Further Reading == | ||
* Kimonis VE, Goldstein AM, Pastakia B, et al. (1991). "Clinical manifestations in 105 persons with nevoid basal cell carcinoma syndrome". [[American Journal of Medical Genetics]]. 41 (3): 250–62. | * Kimonis VE, Goldstein AM, Pastakia B, et al. (1991). "Clinical manifestations in 105 persons with nevoid basal cell carcinoma syndrome". [[American Journal of Medical Genetics]]. 41 (3): 250–62. | ||
* Varga E, Korom I, | * Varga E, Korom I, Rask√≥ I, et al. (2001). "Cryosurgical treatment of eyelid basal cell carcinomas". [[Cancer Letters]]. 173 (1): 1–6. | ||
{{Diseases of the skin and appendages by morphology}} | {{Diseases of the skin and appendages by morphology}} | ||
{{Tumor histology}} | {{Tumor histology}} | ||
{{Skin tumors, epidermis}} | {{Skin tumors, epidermis}} | ||
{{DEFAULTSORT:Basal-Cell Carcinoma}} | {{DEFAULTSORT:Basal-Cell Carcinoma}} | ||
[[Category:Epidermal nevi, neoplasms, and cysts]] | [[Category:Epidermal nevi, neoplasms, and cysts]] | ||
Latest revision as of 19:49, 4 April 2025
Editor-In-Chief: Prab R Tumpati, MD
Obesity, Sleep & Internal medicine
Founder, WikiMD Wellnesspedia &
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| Basal-cell carcinoma | |
|---|---|
| |
| Synonyms | Basal-cell cancer, basal cell epithelioma |
| Pronounce | N/A |
| Specialty | N/A |
| Symptoms | Skin lesion that may appear as a shiny bump, a reddish patch, or a sore that does not heal |
| Complications | Rarely metastasizes, but can cause significant local destruction |
| Onset | Most commonly in adulthood |
| Duration | Chronic |
| Types | N/A |
| Causes | Ultraviolet light exposure, genetic predisposition |
| Risks | Sun exposure, fair skin, radiation therapy, immunosuppression |
| Diagnosis | Skin biopsy |
| Differential diagnosis | Squamous-cell carcinoma, melanoma, sebaceous carcinoma |
| Prevention | Sun protection, avoiding tanning beds |
| Treatment | Surgical excision, Mohs surgery, cryosurgery, topical chemotherapy |
| Medication | N/A |
| Prognosis | Excellent with treatment, but can recur |
| Frequency | Most common form of skin cancer |
| Deaths | N/A |
Basal-cell carcinoma (BCC), also known as basal-cell cancer, is the most common type of skin cancer. It often appears as a painless raised area of skin, which may be shiny with small blood vessels running over it. It may also present as a raised area with ulceration.<ref>
What Is Basal and Squamous Cell Skin Cancer?(link). American Cancer Society.
Accessed 2023-05-04.
</ref> BCC grows slowly and can damage the tissue around it, but it is unlikely to spread to distant areas or result in death.
Causes and Risk Factors[edit]
Basal-cell carcinoma is primarily caused by overexposure to ultraviolet (UV) radiation from sunlight or artificial sources, such as tanning beds. Other risk factors include having light-colored or freckled skin, a personal or family history of BCC, chronic skin inflammation or injury, exposure to radiation or arsenic, and immunosuppression.<ref>
Basal cell carcinoma(link). Mayo Clinic.
Accessed 2023-05-04.
</ref>
Diagnosis[edit]
Diagnosis of BCC often involves a skin examination, followed by a skin biopsy if a lesion is suspected to be cancerous.<ref>
How Is Basal and Squamous Cell Skin Cancer Diagnosed?(link). American Cancer Society.
Accessed 2023-05-04.
</ref>
Treatment[edit]
Treatment options depend on the size, location, and number of lesions. They may include Mohs surgery, simple excision, curettage and desiccation, cryotherapy, radiation therapy, topical medications, or in some cases, oral medications such as hedgehog pathway inhibitors.<ref>
Basal cell carcinoma - Diagnosis and treatment(link). Mayo Clinic.
Accessed 2023-05-04.
</ref>
Prognosis[edit]
While BCC is slow-growing and rarely metastasizes, it can cause significant cosmetic damage and functional impairment, especially when located near the eyes, ears, or nose. Early detection and treatment can reduce the risk of recurrence and prevent complications.<ref>
Basal cell carcinoma: Diagnosis and treatment(link). American Academy of Dermatology Association.
Accessed 2023-05-04.
</ref>
Prevention[edit]
Prevention strategies include reducing sun exposure, using sunscreen, and avoiding tanning beds. Regular skin self-examinations can also help detect this cancer at an early stage.<ref>
Prevention Tips(link). Centers for Disease Control and Prevention.
Accessed 2023-05-04.
</ref>
See Also[edit]
References[edit]
<references group="" responsive="1"></references>
External Links[edit]
- Basal and Squamous Cell Skin Cancer - American Cancer Society
- Skin Cancer (Non-Melanoma) - Cancer.Net
- Basal Cell Carcinoma - American Academy of Dermatology Association
Further Reading[edit]
- Kimonis VE, Goldstein AM, Pastakia B, et al. (1991). "Clinical manifestations in 105 persons with nevoid basal cell carcinoma syndrome". American Journal of Medical Genetics. 41 (3): 250–62.
- Varga E, Korom I, Rask√≥ I, et al. (2001). "Cryosurgical treatment of eyelid basal cell carcinomas". Cancer Letters. 173 (1): 1–6.
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