Marjolin's ulcer

Editor-In-Chief: Prab R Tumpati, MD
Obesity, Sleep & Internal medicine
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Marjolin's ulcer
Synonyms	N/A
Pronounce	N/A
Specialty	N/A
Symptoms	Ulcer, chronic wound, squamous cell carcinoma
Complications	Metastasis, infection
Onset	Years after initial injury or scar formation
Duration	Chronic
Types	N/A
Causes	Chronic inflammation, burn scar, pressure ulcer, venous ulcer
Risks	Chronic wound, scar tissue
Diagnosis	Biopsy, histopathology
Differential diagnosis	Basal cell carcinoma, melanoma, pyoderma gangrenosum
Prevention	Early treatment of chronic wounds, regular monitoring of scars
Treatment	Surgical excision, radiation therapy, chemotherapy
Medication	N/A
Prognosis	Variable, depends on stage and treatment
Frequency	Rare
Deaths	N/A

Marjolin's ulcer of sole of foot

Marjolin's ulcer is a type of skin cancer that develops in areas of the skin that have been previously damaged or scarred. It is named after the French surgeon Jean-Nicolas Marjolin, who first described the condition in the 19th century.

History

The condition was first described by Jean-Nicolas Marjolin in the 19th century. Marjolin was a French surgeon who noticed that some patients developed cancer in areas of the skin that had been previously damaged or scarred.

Causes

Marjolin's ulcer is caused by the transformation of a long-standing wound, burn scar, or other chronic skin condition into a malignant (cancerous) lesion. This process is known as malignant transformation.

Symptoms

The symptoms of Marjolin's ulcer can vary, but often include a non-healing wound or ulcer, pain, bleeding, and sometimes a foul-smelling discharge. The ulcer may also increase in size over time.

Diagnosis

The diagnosis of Marjolin's ulcer is usually made by a biopsy of the affected skin. This involves removing a small sample of tissue and examining it under a microscope to look for cancer cells.

Treatment

The treatment for Marjolin's ulcer typically involves surgery to remove the cancerous tissue. In some cases, radiation therapy or chemotherapy may also be used.

Prognosis

The prognosis for Marjolin's ulcer depends on a number of factors, including the size and location of the ulcer, the type of cancer, and the patient's overall health.

See also

• Skin cancer
• Malignant transformation
• Jean-Nicolas Marjolin

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