Large-cell acanthoma

Large-cell acanthoma (pronunciation: larj-sel a-kan-tho-ma) is a benign skin lesion that typically occurs in elderly individuals. It is characterized by large, pale keratinocytes and is often found on sun-exposed areas of the skin.

Etymology

The term "large-cell acanthoma" is derived from the Greek words "akantos" meaning thorn and "oma" meaning tumor, referring to the thorny appearance of the cells under a microscope. "Large-cell" refers to the size of the keratinocytes, which are larger than normal.

Description

Large-cell acanthoma is a benign skin lesion that is often found on sun-exposed areas of the skin, such as the face and hands. It is characterized by large, pale keratinocytes, which are the cells that make up the outermost layer of the skin. These cells are larger than normal, giving the lesion its name.

Symptoms

The most common symptom of large-cell acanthoma is a single, well-defined, flat or slightly raised patch of skin that is lighter in color than the surrounding skin. The lesion may be asymptomatic, but some individuals may experience mild itching or irritation.

Diagnosis

Diagnosis of large-cell acanthoma is typically made through a skin biopsy, in which a small sample of the lesion is removed and examined under a microscope. The characteristic large, pale keratinocytes are usually sufficient to make a diagnosis.

Treatment

Treatment for large-cell acanthoma is typically not necessary, as the lesion is benign and does not pose a risk to health. However, if the lesion is bothersome or cosmetically undesirable, it can be removed through cryotherapy, laser therapy, or surgical excision.

Related Terms

• Keratinocyte
• Skin lesion
• Skin biopsy
• Cryotherapy
• Laser therapy

External links

• Medical encyclopedia article on Large-cell acanthoma
• Wikipedia's article - Large-cell acanthoma

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