Nevus comedonicus syndrome

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Nevus comedonicus syndrome
Synonyms Comedo nevus syndrome
Pronounce N/A
Specialty N/A
Symptoms Comedo-like lesions, keratin-filled follicular openings
Complications Secondary infection, scarring
Onset Childhood
Duration Chronic
Types N/A
Causes Genetic mutation
Risks
Diagnosis Clinical diagnosis, skin biopsy
Differential diagnosis Epidermal nevus, acne
Prevention N/A
Treatment Topical retinoids, surgical excision, laser therapy
Medication Retinoids, antibiotics
Prognosis N/A
Frequency Rare
Deaths N/A


Definition

A rare, syndromic nevus characterized by the association of typically unilateral, closely arranged, linear, slightly elevated, multiple, nevus comedonicus lesions located usually on the face, neck, trunk or limbs (with or without a central, dark, firm, hyperkeratotic plug and secondary acneiform lesions) with extracutaneous ocular, skeletal, and/or central nervous system abnormalities, such as ipsilateral cataract, corneal erosion, poly-/syndactyly, absent fifth finger, scoliosis, vertebral defects, corpus callosum agenesis, seizures, interhemispheric cyst, intellectual deficiency, and/or developmental delay.

NIH genetic and rare disease info

Nevus comedonicus syndrome is a rare disease.


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