Necrobiosis lipoidica

Editor-In-Chief: Prab R Tumpati, MD
Obesity, Sleep & Internal medicine
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Necrobiosis lipoidica
Synonyms	Necrobiosis lipoidica diabeticorum
Pronounce	N/A
Specialty	Dermatology
Symptoms	Skin lesions, ulceration
Complications	Infection, scarring
Onset	Typically in adulthood
Duration	Chronic
Types	N/A
Causes	Unknown, possibly related to diabetes mellitus
Risks	Diabetes, female gender
Diagnosis	Clinical diagnosis, skin biopsy
Differential diagnosis	Granuloma annulare, rheumatoid nodule, sarcoidosis
Prevention	N/A
Treatment	Topical corticosteroids, intralesional steroid injection, phototherapy
Medication	Corticosteroids, immunosuppressive drugs
Prognosis	N/A
Frequency	Rare
Deaths	N/A

Necrobiosis lipoidica - low magnification

Necrobiosis Lipoidica is a rare chronic skin condition, typically manifesting as shiny, firm, raised skin patches. It is often associated with diabetes mellitus, although the exact cause remains unknown.

Signs and Symptoms

Necrobiosis Lipoidica typically presents as shiny, firm, raised patches on the skin. These patches are often yellowish or reddish-brown in color, and may be surrounded by a thin, pale border. The skin in these areas may be thin and easily damaged, leading to the formation of ulcers.

Causes

The exact cause of Necrobiosis Lipoidica is unknown. However, it is often associated with diabetes mellitus, and is more common in individuals with this condition. Other potential risk factors include trauma, inflammation, and certain autoimmune diseases.

Diagnosis

Diagnosis of Necrobiosis Lipoidica is typically based on the appearance of the skin lesions. A skin biopsy may be performed to confirm the diagnosis and rule out other conditions.

Treatment

Treatment for Necrobiosis Lipoidica is aimed at managing symptoms and preventing complications. This may include the use of topical or injectable corticosteroids, laser therapy, or surgery in severe cases.

Prognosis

The prognosis for individuals with Necrobiosis Lipoidica is generally good, although the condition can cause significant cosmetic concerns and potential complications such as ulceration and infection.

See Also

• Diabetes mellitus
• Skin biopsy
• Corticosteroids

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References

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External Links

• Mayo Clinic - Necrobiosis Lipoidica
• DermNet NZ - Necrobiosis Lipoidica