Necrobiosis lipoidica

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Necrobiosis lipoidica
Necrobiosis lipoidica
Synonyms Necrobiosis lipoidica diabeticorum
Pronounce N/A
Specialty Dermatology
Symptoms Skin lesions, ulceration
Complications Infection, scarring
Onset Typically in adulthood
Duration Chronic
Types N/A
Causes Unknown, possibly related to diabetes mellitus
Risks Diabetes, female gender
Diagnosis Clinical diagnosis, skin biopsy
Differential diagnosis Granuloma annulare, rheumatoid nodule, sarcoidosis
Prevention N/A
Treatment Topical corticosteroids, intralesional steroid injection, phototherapy
Medication Corticosteroids, immunosuppressive drugs
Prognosis N/A
Frequency Rare
Deaths N/A


Necrobiosis lipoidica - low magnification

Necrobiosis Lipoidica is a rare chronic skin condition, typically manifesting as shiny, firm, raised skin patches. It is often associated with diabetes mellitus, although the exact cause remains unknown.

Signs and Symptoms

Necrobiosis Lipoidica typically presents as shiny, firm, raised patches on the skin. These patches are often yellowish or reddish-brown in color, and may be surrounded by a thin, pale border. The skin in these areas may be thin and easily damaged, leading to the formation of ulcers.

Causes

The exact cause of Necrobiosis Lipoidica is unknown. However, it is often associated with diabetes mellitus, and is more common in individuals with this condition. Other potential risk factors include trauma, inflammation, and certain autoimmune diseases.

Diagnosis

Diagnosis of Necrobiosis Lipoidica is typically based on the appearance of the skin lesions. A skin biopsy may be performed to confirm the diagnosis and rule out other conditions.

Treatment

Treatment for Necrobiosis Lipoidica is aimed at managing symptoms and preventing complications. This may include the use of topical or injectable corticosteroids, laser therapy, or surgery in severe cases.

Prognosis

The prognosis for individuals with Necrobiosis Lipoidica is generally good, although the condition can cause significant cosmetic concerns and potential complications such as ulceration and infection.

See Also

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Contributors: Prab R. Tumpati, MD