Restless leg syndrome

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Restless Leg Syndrome

Restless leg syndrome (RLS), also known as Willis-Ekbom disease, is a neurological disorder characterized by an irresistible urge to move one's body to stop uncomfortable or odd sensations. It most commonly affects the legs, but can also affect the arms, torso, and even phantom limbs. Moving the affected body part modulates the sensations, providing temporary relief.

Pronunciation

Restless leg syndrome: /ˈrɛstlɪs lɛg sɪnˈdroʊm/

Etymology

The term "Restless leg syndrome" was first used in the medical literature in 1945 by Swedish neurologist Karl-Axel Ekbom, who also used the term "Willis-Ekbom disease" to describe the condition.

Symptoms

The hallmark symptom of RLS is a desire to move the legs, often accompanied by uncomfortable sensations. Some words used to describe these sensations include: creeping, itching, pulling, creepy-crawly, tugging, or gnawing.

Causes

The exact cause of RLS is unknown. However, it is believed to be related to abnormalities in the dopaminergic system, which controls automatic movements and may also be associated with iron deficiency, kidney failure, or peripheral neuropathy.

Treatment

Treatment for RLS is targeted at easing symptoms. In those with mild to moderate symptoms, lifestyle changes such as increased activity, regular sleep patterns, and decreased use of caffeine, alcohol, and tobacco may be helpful. Medications used include dopamine agonists, benzodiazepines, and opioids.

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