Cataplexy

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Cataplexy

Cataplexy (pronounced: /ˈkætəˌplɛksi/) is a sudden and transient episode of muscle weakness accompanied by full conscious awareness, typically triggered by emotions such as laughing, crying, or terror.

Etymology

The term "cataplexy" originates from the Greek words "kata", meaning "down", and "plexis", meaning "stroke".

Definition

Cataplexy is a condition that causes a person to suddenly feel weak and collapse at moments of strong emotion. It is often associated with Narcolepsy, a long-term neurological disorder that involves a decreased ability to regulate sleep-wake cycles.

Symptoms

Symptoms of cataplexy can range from slurred speech and drooping eyelids to total body collapse, depending on the emotional trigger and the individual's condition. These symptoms can last from a few seconds to several minutes.

Causes

Cataplexy is caused by an autoimmune destruction of hypocretin neurons in the brain. Hypocretin is a neurotransmitter that regulates arousal, wakefulness, and appetite. The lack of it leads to instability between sleep and wake states, causing symptoms of cataplexy.

Treatment

Treatment for cataplexy involves medications such as antidepressants and sodium oxybate. These medications help to regulate sleep patterns and manage symptoms.

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