Meige's syndrome

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Obesity, Sleep & Internal medicine
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Meige's syndrome
Synonyms	Brueghel syndrome, oral-facial dystonia
Pronounce	N/A
Specialty	N/A
Symptoms	Blepharospasm, oromandibular dystonia, facial muscle spasms
Complications	Difficulty speaking, difficulty eating, social anxiety
Onset	Middle age
Duration	Chronic
Types	N/A
Causes	Unknown, possibly genetic and environmental factors
Risks	Family history of dystonia, stress, fatigue
Diagnosis	Clinical diagnosis, neurological examination
Differential diagnosis	Hemifacial spasm, tardive dyskinesia, Parkinson's disease
Prevention	N/A
Treatment	Botulinum toxin injections, medications, surgery
Medication	Anticholinergics, muscle relaxants
Prognosis	Variable, often requires ongoing treatment
Frequency	Rare
Deaths	N/A

Meige's Syndrome is a rare neurological movement disorder characterized by involuntary and often forceful contractions of the muscles of the jaw and tongue (dystonia) and involuntary muscle spasms and contractions or tics of the muscles around the eyes (blepharospasm).

Symptoms

The symptoms of Meige's Syndrome typically begin between the ages of 30 and 70 years, and may include involuntary eye blinking, forceful closing of the eyes, jaw muscle discomfort, difficulty opening the mouth, and speech and swallowing difficulties due to muscle spasms. The severity and expression of these symptoms can vary widely among affected individuals.

Causes

The exact cause of Meige's Syndrome is unknown. However, it is believed to result from a combination of genetic and environmental factors. Some researchers believe that it may be related to abnormalities or damage in certain areas of the brain that control movement.

Diagnosis

Diagnosis of Meige's Syndrome is based on a thorough clinical evaluation, a detailed patient history, and a variety of specialized tests. These tests may include blood tests, imaging studies such as MRI or CT scan, and possibly a lumbar puncture.

Treatment

There is currently no cure for Meige's Syndrome. Treatment is symptomatic and may include medications, botulinum toxin injections, deep brain stimulation, and/or surgery. Physical therapy may also be beneficial for some individuals.

Prognosis

The prognosis for individuals with Meige's Syndrome varies. While the condition is not life-threatening, it can significantly impact an individual's quality of life. However, with appropriate treatment and management, many individuals with Meige's Syndrome are able to lead productive lives.

See Also

• Dystonia
• Blepharospasm
• Neurological Disorders

References

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