Comedo

Editor-In-Chief: Prab R Tumpati, MD
Obesity, Sleep & Internal medicine
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Comedo
Synonyms	Blackhead, whitehead
Pronounce	N/A
Specialty	N/A
Symptoms	Small bumps on the skin, often on the face, neck, back, and shoulders
Complications	Acne
Onset	Puberty
Duration	Variable
Types	N/A
Causes	Sebaceous gland blockage
Risks	Hormonal changes, oily skin, cosmetic use
Diagnosis	Physical examination
Differential diagnosis	Folliculitis, milia
Prevention	Regular skin cleansing, avoiding oily cosmetics
Treatment	Topical retinoids, benzoyl peroxide, salicylic acid
Medication	N/A
Prognosis	N/A
Frequency	Common, especially in adolescents
Deaths	N/A

A comedo is a form of primary acne lesion, which presents as a small bump or spot on the skin. It arises due to the blockage of a hair follicle by excessive sebum and dead skin cells.<ref>

Acne Vulgaris(link). {{{website}}}. StatPearls.

</ref> Comedones can manifest in two major forms: open (blackheads) and closed (whiteheads). Despite being benign in nature, comedones can lead to psychological distress due to their impact on appearance.<ref>

Comedone Acne(link). {{{website}}}. PubMed Central.

</ref>

Nose with Blackhead 2009

Pathophysiology

The formation of a comedo begins with the plugging of a hair follicle. This is often initiated by an overproduction of sebum, an oily substance produced by the sebaceous glands, in conjunction with an accumulation of dead skin cells. These factors lead to the formation of a keratinous plug, creating a favorable environment for the growth of the bacterium Cutibacterium acnes. The metabolic activity of this bacterium may further contribute to follicular obstruction and inflammation, leading to the development of visible acne lesions.<ref>,

 Pathophysiology of acne, 
 Journal of the European Academy of Dermatology and Venereology, 
 2018,
 
 
 
 
 
 
 Full text,</ref>

Blausen Skin Pores

Types of Comedones

Comedos Nose 01

Comedones are primarily classified into two types: Open comedones (blackheads): These are dilated hair follicles filled with keratin, bacteria, and sebum. The black color is due to the oxidation of sebum rather than dirt. They are usually painless. Closed comedones (whiteheads): These are smaller, flesh-colored papules that are filled with sebum and skin debris. They are covered by a thin layer of skin which prevents the contents from oxidizing and becoming black.<ref>

Acne and Its Management(link). {{{website}}}. PubMed Central.

</ref>

Diagnosis and Treatment

Diagnosis of comedones is typically based on clinical examination. The appearance of blackheads and whiteheads on the skin is usually indicative of the condition.<ref>

Acne(link). {{{website}}}. DermNet NZ.

</ref> Treatment for comedones primarily involves topical applications aimed at unclogging pores and reducing sebum production. These include retinoids, salicylic acid, and benzoyl peroxide. In some cases, extraction using a comedone extractor may be performed by a dermatologist. Lifestyle modifications such as maintaining proper skin hygiene and a balanced diet can also help manage the condition.<ref>

Acne: Tips for managing(link). {{{website}}}. American Academy of Dermatology Association.

</ref>

See Also

• Acne vulgaris
• Hair follicle
• Sebaceous gland
• Cutibacterium acnes

References

<references />

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