Palmoplantar keratoderma

Palmoplantar keratoderma (pronunciation: pal-mo-plan-tar ker-a-der-ma) is a medical condition characterized by the thickening of the skin on the palms of the hands and soles of the feet. The term is derived from the Greek words palme (palm), plantar (sole), and keratoderma (horny layer of the skin).

Definition

Palmoplantar keratoderma refers to a group of disorders characterized by abnormal thickening of the skin on the palms and soles. It is often associated with other skin abnormalities and systemic diseases.

Symptoms

The primary symptom of palmoplantar keratoderma is the thickening of the skin on the palms and soles. This can lead to discomfort, pain, and difficulty walking or using the hands. Other symptoms may include redness, scaling, and cracks in the skin.

Causes

Palmoplantar keratoderma can be caused by a variety of factors, including genetic mutations, environmental factors, and certain systemic diseases. It can be inherited in an autosomal dominant or recessive manner.

Treatment

Treatment for palmoplantar keratoderma typically involves the use of topical creams and ointments to soften the skin and reduce thickening. In severe cases, systemic medications may be used.

Related Terms

• Epidermis
• Dermatology
• Genetic mutation
• Autosomal dominant
• Autosomal recessive

See Also

• List of skin conditions
• List of genetic disorders

External links

• Medical encyclopedia article on Palmoplantar keratoderma
• Wikipedia's article - Palmoplantar keratoderma

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