Subacute cutaneous lupus erythematosus

Subacute cutaneous lupus erythematosus
Synonyms	SCLE
Pronounce	N/A
Specialty	N/A
Symptoms	Skin rash, photosensitivity, arthralgia
Complications	Systemic lupus erythematosus, nephritis
Onset	Typically between ages 15 and 50
Duration	Chronic
Types	N/A
Causes	Autoimmune disease
Risks	Genetic predisposition, ultraviolet light exposure, certain medications
Diagnosis	Clinical examination, skin biopsy, serological tests
Differential diagnosis	Psoriasis, eczema, rosacea
Prevention	N/A
Treatment	Topical corticosteroids, antimalarials, immunosuppressants
Medication	Hydroxychloroquine, methotrexate, prednisone
Prognosis	Variable, can be managed with treatment
Frequency	Rare
Deaths	N/A

Subacute cutaneous lupus erythematosus (SCLE) is a subtype of lupus erythematosus, an autoimmune disease. It is characterized by skin lesions that appear on areas of the body exposed to the sun. The lesions may be either annular (ring-shaped) or psoriasiform (resembling psoriasis).

Signs and Symptoms

Patients with SCLE typically present with skin lesions that are either annular or psoriasiform. These lesions are photosensitive, meaning they worsen with exposure to sunlight. Other symptoms may include fatigue, joint pain, and fever.

Causes

The exact cause of SCLE is unknown, but it is believed to be an autoimmune disorder. This means that the body's immune system mistakenly attacks healthy tissue. Certain factors may trigger the onset of the disease, such as exposure to sunlight, certain medications, and viral infections.

Diagnosis

Diagnosis of SCLE is based on the patient's clinical presentation and laboratory tests. A skin biopsy may be performed to confirm the diagnosis. Blood tests may reveal the presence of certain antibodies that are commonly found in patients with SCLE.

Treatment

Treatment for SCLE typically involves avoiding sun exposure and using sun-protective measures. Medications may also be prescribed to manage symptoms and prevent flare-ups. These may include topical corticosteroids, antimalarial drugs, and immunosuppressive agents.

Prognosis

The prognosis for patients with SCLE is generally good, as the disease is usually less severe than other forms of lupus erythematosus. However, patients may experience periods of remission and relapse.

See Also

• Lupus erythematosus
• Autoimmune diseases
• Skin biopsy
• Corticosteroids
• Antimalarial drugs

References

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