PUVA therapy

PUVA therapy is a type of phototherapy used to treat various skin diseases. The name is an acronym for the two components of the treatment: Psoralen and UVA light.

Overview

Psoralen is a medication that makes the skin more sensitive to light. It is taken orally or applied topically before exposure to UVA light. The UVA light then activates the psoralen, which inhibits the growth of rapidly dividing cells, such as those found in skin diseases.

Uses

PUVA therapy is used to treat a variety of skin conditions, including psoriasis, vitiligo, eczema, and cutaneous T-cell lymphoma. It is typically used when these conditions have not responded to other treatments.

Procedure

The patient takes psoralen orally or applies it topically, then waits for a specific amount of time before being exposed to UVA light. The light exposure is carefully controlled and gradually increased over the course of treatment.

Side effects

Possible side effects of PUVA therapy include nausea, itching, and burning. Long-term risks include premature aging of the skin and skin cancer.

See also

• Phototherapy
• Psoriasis
• Vitiligo
• Eczema
• Cutaneous T-cell lymphoma

References

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