Dermatopathia pigmentosa reticularis

From WikiMD.org
Jump to navigation Jump to search

Dermatopathia Pigmentosa Reticularis (pronunciation: der-ma-to-path-ia pig-men-tosa re-tic-u-laris) is a rare, genetic skin disorder characterized by hyperpigmentation, noncicatricial alopecia, and nail dystrophy. It is a form of Ectodermal Dysplasia.

Etymology

The term Dermatopathia Pigmentosa Reticularis originates from the Greek words derma meaning skin, pathos meaning disease, pigmentosa referring to pigmentation, and reticularis indicating the reticular or net-like pattern of the skin changes observed in this condition.

Symptoms

The primary symptoms of Dermatopathia Pigmentosa Reticularis include Hyperpigmentation, Noncicatricial Alopecia, and Nail Dystrophy. Hyperpigmentation refers to the darkening of the skin, while noncicatricial alopecia refers to hair loss that does not lead to scarring. Nail dystrophy refers to any deformity or disease related to the nails.

Causes

Dermatopathia Pigmentosa Reticularis is caused by mutations in the KRT14 gene. This gene provides instructions for making a protein that is a crucial component of Keratinocytes, the cells that make up most of the skin's outer layer.

Diagnosis

Diagnosis of Dermatopathia Pigmentosa Reticularis is based on clinical examination, patient history, and confirmed by genetic testing of the KRT14 gene.

Treatment

There is currently no cure for Dermatopathia Pigmentosa Reticularis. Treatment is symptomatic and supportive, focusing on managing the individual symptoms and complications of the disorder.

See Also

External links

Esculaap.svg

This WikiMD dictionary article is a stub. You can help make it a full article.


Languages: - East Asian 中文, 日本, 한국어, South Asian हिन्दी, Urdu, বাংলা, తెలుగు, தமிழ், ಕನ್ನಡ,
Southeast Asian Indonesian, Vietnamese, Thai, မြန်မာဘာသာ, European español, Deutsch, français, русский, português do Brasil, Italian, polski