Keratolytics

Keratolytics

Keratolytics (pronunciation: /ˌkɛrəˌtoʊlɪˈtɪks/) are a type of medication or treatment that is used to soften and break down the stratum corneum, the outermost layer of the skin. This process helps to shed excess skin cells and can be used in the treatment of various skin conditions, including psoriasis, eczema, corns, and calluses.

Etymology

The term "keratolytic" is derived from the Greek words "keras," meaning horn, and "lysis," meaning loosening or breaking down. This refers to the medication's ability to break down the tough, horn-like outer layer of the skin.

Mechanism of Action

Keratolytics work by dissolving the intercellular matrix of the skin's stratum corneum, promoting desquamation of scaly skin, eventually resulting in softening and shedding of the horny outer layer.

Types of Keratolytics

There are several types of keratolytics, including:

• Salicylic Acid: This is a beta hydroxy acid that is often used in the treatment of acne, psoriasis, and other skin conditions. It works by breaking down the keratin in the skin, allowing for the removal of dead skin cells.

• Urea: This is a compound that is naturally found in the human body. In keratolytic treatments, it is used to hydrate and exfoliate the skin.

• Lactic Acid: This alpha hydroxy acid is used to moisturize and exfoliate the skin, helping to remove dead skin cells and promote the growth of new ones.

Side Effects

Like all medications, keratolytics can have side effects. These can include skin irritation, redness, and peeling. It is important to use these medications as directed by a healthcare professional to minimize the risk of side effects.

Related Terms

• Keratosis: This is a condition characterized by an overgrowth of the top layer of skin. Keratolytics can be used to treat this condition.

• Desquamation: This is the process of shedding or peeling of dead skin cells. Keratolytics promote this process.

• Stratum Corneum: This is the outermost layer of the skin, which keratolytics work to break down and shed.

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