Tyrosol

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Tyrosol

Chemical structure of Tyrosol

Tyrosol is a naturally occurring phenolic compound found in a variety of plants and foods, most notably in olive oil. It is a type of phenylethanoid, which is a class of phenolic compounds characterized by a hydroxyphenethyl structure.

Chemical Structure

Tyrosol is chemically known as 4-(2-hydroxyethyl)phenol. Its molecular formula is C8H10O2. The structure consists of a phenol group attached to a two-carbon hydroxyethyl side chain. This structure is responsible for its antioxidant properties.

Sources

Tyrosol is predominantly found in olive oil, which is a staple of the Mediterranean diet. It is also present in other plants and foods such as wine, green tea, and certain herbs. The concentration of tyrosol in these sources can vary depending on factors such as the variety of the plant, climate, and processing methods.

Biological Activity

Tyrosol is known for its antioxidant properties, which help in neutralizing free radicals and reducing oxidative stress in the body. This activity is beneficial in protecting cells from damage and may contribute to the health benefits associated with the Mediterranean diet.

Cardiovascular Health

Studies suggest that tyrosol may have a positive impact on cardiovascular health. It is believed to help in reducing inflammation and improving endothelial function, which are important factors in maintaining healthy blood vessels.

Neuroprotective Effects

Tyrosol has been studied for its potential neuroprotective effects. It may help in protecting neurons from oxidative damage and apoptosis, which are processes involved in neurodegenerative diseases such as Alzheimer's disease and Parkinson's disease.

Metabolism

After ingestion, tyrosol is absorbed in the small intestine and metabolized in the liver. It is converted into various metabolites, which are then excreted in the urine. The bioavailability of tyrosol can be influenced by factors such as the food matrix and gut microbiota.

Related Compounds

Tyrosol is structurally related to other phenolic compounds such as hydroxytyrosol, which is also found in olive oil and has similar antioxidant properties. These compounds are collectively known as polyphenols and contribute to the health benefits of plant-based diets.

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Contributors: Prab R. Tumpati, MD