Primary aldosteronism

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Primary Aldosteronism

Primary Aldosteronism (pronunciation: al-dos-tuh-roh-niz-uhm), also known as Conn's syndrome, is a hormonal disorder that leads to high blood pressure. The condition is characterized by the overproduction of the hormone aldosterone by the adrenal glands. This overproduction leads to the retention of sodium and loss of potassium in the body, which can result in high blood pressure (hypertension).

Etymology

The term "Primary Aldosteronism" is derived from the hormone "aldosterone" that is primarily involved in the condition, and the suffix "-ism" which denotes a condition or disease. The term "Conn's syndrome" is named after Dr. Jerome W. Conn who first described the condition in 1955.

Symptoms

The symptoms of Primary Aldosteronism can vary, but often include:

  • High blood pressure (hypertension)
  • Muscle weakness and cramps
  • Excessive thirst and urination
  • Headaches
  • Fatigue

Diagnosis

Diagnosis of Primary Aldosteronism typically involves blood and urine tests to measure levels of aldosterone and renin, a hormone that regulates blood pressure. Imaging tests such as CT scans or MRI may also be used to check for abnormalities in the adrenal glands.

Treatment

Treatment for Primary Aldosteronism usually involves medications to block the action of aldosterone, or surgery to remove the overactive adrenal gland. Lifestyle changes such as reducing sodium intake and maintaining a healthy weight can also help manage the condition.

Related Terms

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