Myxedema coma

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Myxedema Coma

Myxedema coma (pronunciation: mix-uh-DEE-muh KOH-muh) is a rare but life-threatening condition that represents extreme hypothyroidism. It is characterized by a severe decrease in the level of thyroid hormones in the body, leading to a significant drop in metabolic functions.

Etymology

The term "myxedema" is derived from the Greek words "myxa" meaning mucus, and "oidema" meaning swelling. The term "coma" is derived from the Greek word "koma," which means deep sleep.

Symptoms

The symptoms of myxedema coma are an extreme form of the symptoms of Hypothyroidism. These include:

  • Intense cold intolerance
  • Decreased mental function
  • Low body temperature
  • Difficulty breathing
  • Low blood pressure
  • Low blood sugar
  • Unresponsiveness

Causes

Myxedema coma is usually triggered by a stressor such as infection, stroke, trauma, or certain medications in individuals with untreated or poorly managed Hypothyroidism.

Diagnosis

Diagnosis of myxedema coma is based on clinical presentation and confirmed by laboratory tests showing very low levels of thyroid hormones (T3 and T4) and high levels of thyroid-stimulating hormone (TSH).

Treatment

Treatment of myxedema coma involves immediate hospitalization and intensive care. It typically includes administration of intravenous thyroid hormones and management of the precipitating factors.

Prognosis

The prognosis of myxedema coma is poor, with a high mortality rate even with treatment. Early detection and treatment can improve the prognosis.

See Also

External links

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