Hashitoxicosis
Hashitoxicosis is a condition that is often associated with Hashimoto's thyroiditis, a common autoimmune disease that affects the thyroid gland. It is characterized by a transient period of hyperthyroidism (overactive thyroid) symptoms, which can include rapid heart rate, weight loss, and anxiety, among others.
Causes
Hashitoxicosis is caused by the destruction of thyroid cells by the immune system in patients with Hashimoto's thyroiditis. This destruction leads to the release of preformed thyroid hormone into the bloodstream, causing a temporary increase in thyroid hormone levels and symptoms of hyperthyroidism.
Symptoms
The symptoms of hashitoxicosis are similar to those of hyperthyroidism and can include:
- Rapid heart rate
- Weight loss
- Anxiety
- Tremors
- Increased sensitivity to heat
- Fatigue
- Difficulty sleeping
Diagnosis
The diagnosis of hashitoxicosis can be challenging as it can mimic other conditions. It is often diagnosed based on the patient's symptoms, medical history, and laboratory tests. These tests can include thyroid function tests to measure the levels of thyroid hormones in the blood and antibody tests to detect the presence of antibodies against the thyroid gland.
Treatment
The treatment for hashitoxicosis is typically aimed at managing the symptoms. This can include beta-blockers to slow down the heart rate and relieve symptoms such as anxiety and tremors. Once the hyperthyroid phase is over, patients may require treatment for hypothyroidism (underactive thyroid), which can include thyroid hormone replacement therapy.
See also
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Contributors: Prab R. Tumpati, MD