CBV (chemotherapy)

For other uses, see CBV (disambiguation).

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CBV refers to Cytoxan (cyclophosphamide), BCNU (carmustine), and VP-16 (etoposide), three drugs in a chemotherapy regimen commonly given to lymphoma patients in conjunction with stem cell therapy.<ref>Skeel, Roland T. Handbook of Cancer Chemotherapy, 6th Edition. Philadelphia: Lippincott Williams & Wilkins, 2003. Page 172-3, Table 5.4: "Common preparative regimens for high-dose therapy without total-body irradiation."</ref>

CBV is usually given in high doses to patients who have relapsed or who have refractory disease and cannot benefit from standard chemotherapy. Since a patient's bone marrow is virtually guaranteed not to survive a course of CBV, the receiving patient must receive a transplant (allogeneic or autologous, depending on his or her condition) of stem cells (formerly referred to as a bone marrow transplant) to replace the patient's own hemopoietic ("blood-forming") stem cells.<ref>"Alternatives to Blood Transfusions for Patients." Penn Online Today. Jan./Feb. 2004. <http://www.pennhealth.com/phys_forum/pto/jan_feb04/blood.html"></ref>

See also

• Cancer
• Chemotherapy
• Lymphoma
• Stem cells
• Bone marrow transplant

References

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