Nandrolone undecanoate: Difference between revisions

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'''Nandrolone undecanoate''' is a [[synthetic anabolic steroid]] that is derived from [[testosterone]]. It is used in the treatment of [[osteoporosis]], [[anemia]], and some forms of [[neoplasia]] including [[breast cancer]], and also acts as a progestin-based contraceptive.
== Nandrolone Undecanoate ==


==Chemistry==
[[File:Nandrolone_undecylate.svg|thumb|right|Chemical structure of Nandrolone Undecanoate]]
Nandrolone undecanoate, also known as 19-nortestosterone 17β-undecanoate, is a synthetic [[estrane]] steroid and a derivative of [[testosterone]]. It is more specifically a derivative of 19-nortestosterone (nandrolone). The steroid is a lipophilic compound that is transported in the bloodstream and stored in fat depots.


==Pharmacology==
'''Nandrolone undecanoate''' is an [[anabolic steroid]] and a [[nandrolone]] [[ester]]. It is used in [[medicine]] and [[veterinary medicine]] to promote [[muscle growth]] and to treat certain medical conditions. Nandrolone undecanoate is known for its long-acting properties and is administered via [[intramuscular injection]].
Nandrolone undecanoate is a [[prodrug]] of nandrolone, being converted in the body by [[esterases]] into nandrolone, which is then metabolized by [[enzymes]] in the liver. The drug has a very long duration of action, with a half-life of up to one month.  


==Medical uses==
== Pharmacology ==
Nandrolone undecanoate is used in the treatment of [[osteoporosis]], [[anemia]], and some forms of [[neoplasia]] including [[breast cancer]]. It is also used as a [[progestin-based contraceptive]] in combination with an [[estrogen]].


==Side effects==
Nandrolone undecanoate is a [[prodrug]] of nandrolone, meaning it is converted into the active form, nandrolone, in the body. Nandrolone is a [[synthetic]] [[anabolic-androgenic steroid]] (AAS) that mimics the effects of [[testosterone]]. It has a high [[anabolic]] to [[androgenic]] ratio, which makes it effective for promoting muscle growth with fewer androgenic side effects compared to testosterone.
The side effects of nandrolone undecanoate are similar to those of other [[anabolic steroids]]. These can include [[acne]], [[gynecomastia]], [[edema]], [[weight gain]], [[insomnia]], [[mood changes]], [[hair loss]], [[libido]] changes, and [[liver damage]].  


==See also==
=== Mechanism of Action ===
* [[List of androgens/anabolic steroids]]
* [[List of progestogen esters]]


Nandrolone undecanoate works by binding to [[androgen receptors]] in muscle tissue, which leads to an increase in [[protein synthesis]] and muscle growth. It also enhances [[nitrogen retention]] in muscles, which is crucial for muscle repair and growth.
== Medical Uses ==
Nandrolone undecanoate is used in the treatment of various medical conditions, including:
* [[Anemia]]
* [[Osteoporosis]]
* [[Cachexia]] associated with chronic illness
* Certain types of [[breast cancer]]
== Side Effects ==
Like other anabolic steroids, nandrolone undecanoate can cause a range of side effects. These may include:
* [[Acne]]
* [[Gynecomastia]]
* [[Increased body hair]]
* [[Voice deepening]]
* [[Liver damage]]
* [[Cardiovascular issues]]
== Legal Status ==
Nandrolone undecanoate is a controlled substance in many countries due to its potential for abuse and side effects. It is classified as a Schedule III controlled substance in the United States.
== Related Pages ==
* [[Anabolic steroid]]
* [[Nandrolone]]
* [[Testosterone]]
* [[Androgen receptor]]
{{Anabolic steroids}}
[[Category:Anabolic steroids]]
[[Category:Androgens and anabolic steroids]]
[[Category:Androgens and anabolic steroids]]
[[Category:Progestogens]]
[[Category:Prodrugs]]
[[Category:Prodrugs]]
[[Category:World Anti-Doping Agency prohibited substances]]
{{Anabolic steroid-stub}}
{{Pharma-stub}}

Latest revision as of 16:30, 16 February 2025

Nandrolone Undecanoate[edit]

Chemical structure of Nandrolone Undecanoate

Nandrolone undecanoate is an anabolic steroid and a nandrolone ester. It is used in medicine and veterinary medicine to promote muscle growth and to treat certain medical conditions. Nandrolone undecanoate is known for its long-acting properties and is administered via intramuscular injection.

Pharmacology[edit]

Nandrolone undecanoate is a prodrug of nandrolone, meaning it is converted into the active form, nandrolone, in the body. Nandrolone is a synthetic anabolic-androgenic steroid (AAS) that mimics the effects of testosterone. It has a high anabolic to androgenic ratio, which makes it effective for promoting muscle growth with fewer androgenic side effects compared to testosterone.

Mechanism of Action[edit]

Nandrolone undecanoate works by binding to androgen receptors in muscle tissue, which leads to an increase in protein synthesis and muscle growth. It also enhances nitrogen retention in muscles, which is crucial for muscle repair and growth.

Medical Uses[edit]

Nandrolone undecanoate is used in the treatment of various medical conditions, including:

Side Effects[edit]

Like other anabolic steroids, nandrolone undecanoate can cause a range of side effects. These may include:

Legal Status[edit]

Nandrolone undecanoate is a controlled substance in many countries due to its potential for abuse and side effects. It is classified as a Schedule III controlled substance in the United States.

Related Pages[edit]