Regadenoson
Regadenoson
Regadenoson (pronounced reh-guh-DEN-oh-son) is a pharmacological agent used in stress testing for patients who cannot exercise adequately. It is a selective adenosine A2A receptor agonist.
Etymology
The name "Regadenoson" is derived from the words "adenosine", which is a chemical found in all human cells, and "regaden", which is a prefix used in pharmaceutical naming to denote regulatory action.
Usage
Regadenoson is used primarily in myocardial perfusion imaging, in which it is administered to dilate the coronary arteries before the imaging procedure. This allows for better visualization of the arteries and can help identify areas of reduced blood flow.
Mechanism of Action
Regadenoson works by stimulating the adenosine A2A receptors, which leads to vasodilation. This increases blood flow in the coronary arteries, making it easier to identify any blockages or areas of reduced blood flow during imaging procedures.
Related Terms
- Adenosine: A chemical found in all human cells that plays a crucial role in energy transfer and signal transduction.
- Coronary arteries: The blood vessels that supply the heart muscle with oxygen and nutrients.
- Myocardial perfusion imaging: A type of medical imaging used to assess the blood flow to the heart muscle.
- Vasodilation: The widening of blood vessels, which decreases blood pressure.
Side Effects
Common side effects of Regadenoson include shortness of breath, headache, flushing, chest discomfort, and gastrointestinal discomfort. More serious side effects, though rare, can include heart attack, stroke, and cardiac arrest.
Contraindications
Regadenoson should not be used in patients with certain heart conditions, such as unstable angina or severe heart block. It should also be used with caution in patients with asthma or other respiratory conditions, as it can cause shortness of breath.
External links
- Medical encyclopedia article on Regadenoson
- Wikipedia's article - Regadenoson
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