ZM-241,385
ZM-241,385 is a potent and selective adenosine receptor antagonist, specifically targeting the adenosine A2A receptor. It is widely used in pharmacological research to study the role of adenosine receptors in various physiological and pathological processes.
Chemical Properties[edit]
ZM-241,385 is a synthetic compound with a complex chemical structure. It is known for its high affinity and selectivity towards the adenosine A2A receptor, making it a valuable tool in neuroscience and cardiovascular research.
Mechanism of Action[edit]
ZM-241,385 functions by binding to the adenosine A2A receptor, thereby inhibiting the action of adenosine, a neurotransmitter that plays a crucial role in regulating neurotransmission, vasodilation, and immune response. By blocking this receptor, ZM-241,385 can modulate various physiological responses, making it useful in studying conditions such as Parkinson's disease, ischemia, and inflammation.
Applications in Research[edit]
Neuroscience[edit]
In neuroscience, ZM-241,385 is used to investigate the role of adenosine A2A receptors in neurodegenerative diseases like Parkinson's disease. Studies have shown that antagonism of these receptors can have neuroprotective effects, potentially offering therapeutic benefits.
Cardiovascular Research[edit]
ZM-241,385 is also employed in cardiovascular research to explore its effects on vasodilation and myocardial ischemia. By blocking the adenosine A2A receptor, researchers can better understand the mechanisms underlying cardiovascular diseases and develop new therapeutic strategies.
Immunology[edit]
In the field of immunology, ZM-241,385 is used to study the role of adenosine A2A receptors in modulating the immune response. This research is crucial for developing treatments for inflammatory diseases and autoimmune disorders.
Safety and Handling[edit]
As with any research chemical, proper safety protocols must be followed when handling ZM-241,385. It should be used in a controlled laboratory environment, and appropriate personal protective equipment (PPE) should be worn to prevent exposure.
See Also[edit]
References[edit]
External Links[edit]
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