Choroid plexus papilloma

Choroid plexus papilloma
Synonyms	Papilloma of the choroid plexus
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Field	Neurosurgery
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Choroid plexus papilloma, also known as papilloma of the choroid plexus, is a rare benign neuroepithelial intraventricular WHO grade I lesion found in the choroid plexus.<ref name="pmid10940770">,

 Management of choroid plexus tumours in children: 20 years experience at a single neurosurgical centre, 
 Pediatr Neurosurg, 
 
 Vol. 32(Issue: 4),
 pp. 192–9,
 DOI: 10.1159/000028933,
 PMID: 10940770,
 
 
 Full text,</ref>  It leads to increased cerebrospinal fluid production, thus causing increased intracranial pressure and hydrocephalus.<ref name="AdunkaBuchman2010">, 
  
 Otology, Neurotology, and Lateral Skull Base Surgery: An Illustrated Handbook. online version, 
  
 Thieme, 
  
  
  
 ISBN 978-3-13-149621-8, 
  
  
  
 Pages: 353–,</ref>

Choroid plexus papilloma occurs in the lateral ventricles of children and in the fourth ventricle of adults. This is unlike most other pediatric tumors and adult tumors, in which the locations of the tumors is reversed. In children, brain tumors are usually found in the infratentorial region and in adults, brain tumors are usually found in the supratentorial space. The relationship is reversed for choroid plexus papillomas.

Signs and symptoms

Signs of the tumor resulting from increased intracranial pressure are present in 91% of patients, with vomiting, homonymous visual field defects and headache being the most common symptoms. Other symptoms are ear ringing and dizziness.

Pathophysiology

The tumor is neuroectodermal in origin and similar in structure to a normal choroid plexus. They may be created by epithelial cells of the choroid plexus.

• Micrograph of a choroid plexus papilloma. H&E stain.
  Micrograph of a choroid plexus papilloma. H&E stain.
• Plexuspapillom Detail
  Plexuspapillom Detail
• Plexuspapillom Overview
  Plexuspapillom Overview

Treatment

Choroid plexus papillomas are benign tumors that are usually cured by surgery; malignant progression has been rarely reported.

Epidemiology

Internationally tumors of the choroid plexus are rare, accounting for 0.4-0.6% of all intracranial neoplasms. It most commonly affects young children under the age of 5 with a mean patient age of 5.2 years.

External links

• Choroid Plexus Papilloma MRI, CT, and pathology images from MedPix

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