Pleomorphic xanthoastrocytoma

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Pleomorphic xanthoastrocytoma (pronunciation: pleo-morphic xantho-astro-cytoma) is a rare type of brain tumor that primarily affects children and young adults.

Etymology

The term Pleomorphic xanthoastrocytoma is derived from the Greek words pleio (more), morphe (form), xanthos (yellow), astro (star), and cytoma (tumor). This refers to the tumor's characteristic of having more forms, its yellowish color due to lipid accumulation, its star-shaped astrocytes, and its nature as a tumor.

Description

Pleomorphic xanthoastrocytoma is a neoplasm that originates from astrocytes, the star-shaped cells that make up the supportive tissue of the brain. This tumor is typically benign (grade I or II) but can sometimes behave in a malignant manner (grade III or IV). The tumor is often located in the cerebral cortex, and symptoms can include seizures, headaches, and neurological deficits.

Diagnosis

Diagnosis of pleomorphic xanthoastrocytoma is typically made through a combination of magnetic resonance imaging (MRI), computed tomography (CT) scans, and histopathological examination of the tumor tissue.

Treatment

Treatment for pleomorphic xanthoastrocytoma typically involves surgical removal of the tumor. In some cases, radiation therapy or chemotherapy may be used as an adjunct to surgery or when surgery is not possible.

Prognosis

The prognosis for individuals with pleomorphic xanthoastrocytoma is generally favorable, with a 5-year survival rate of approximately 70%. However, the prognosis can vary depending on factors such as the individual's age, the location and size of the tumor, and the extent of surgical resection.

See also

External links

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