Cloxotestosterone acetate: Difference between revisions
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Cloxotestosterone Acetate | |||
[[ | [[File:Cloxotestosterone acetate.svg|thumb|Chemical structure of Cloxotestosterone acetate]] | ||
'''Cloxotestosterone acetate''' is a synthetic androgenic steroid and derivative of testosterone. It | '''Cloxotestosterone acetate''' is a synthetic anabolic-androgenic steroid (AAS) and a derivative of testosterone. It is an ester of cloxotestosterone, which is a chlorinated form of testosterone. This compound was developed for potential use in androgen replacement therapy and other medical applications, but it is not widely used in clinical practice. | ||
== Chemical Properties == | ==Chemical Structure and Properties== | ||
Cloxotestosterone acetate is a | Cloxotestosterone acetate is characterized by the presence of a chlorine atom at the 4-position of the steroid nucleus and an acetate ester at the 17β-hydroxyl group. The chemical structure can be represented as follows: | ||
* IUPAC name: (17β)-4-Chloroandrost-4-en-17-ol-3-one acetate | |||
* Molecular formula: C21H29ClO3 | |||
* | * Molecular weight: 364.91 g/mol | ||
The presence of the acetate ester increases the lipophilicity of the molecule, allowing for a slower release and prolonged duration of action when administered intramuscularly. | |||
==Pharmacology== | |||
Cloxotestosterone acetate acts as an agonist of the androgen receptor, similar to other anabolic steroids. It promotes protein synthesis and muscle growth, and it can also influence secondary sexual characteristics. The chlorination at the 4-position is intended to modify the activity and metabolism of the steroid, potentially reducing its androgenic effects while maintaining anabolic properties. | |||
== | ==Medical Uses== | ||
Although cloxotestosterone acetate was developed for medical use, it is not commonly used in clinical practice. Potential applications include: | |||
* Treatment of male hypogonadism | |||
* Androgen replacement therapy | |||
* Management of certain types of anemia | |||
However, due to the availability of other more established and well-studied anabolic steroids, cloxotestosterone acetate is rarely prescribed. | |||
== | ==Side Effects== | ||
As with other anabolic steroids, cloxotestosterone acetate can cause a range of side effects, particularly with long-term use or at high doses. These may include: | |||
[[ | * Virilization in women | ||
[[ | * Acne and oily skin | ||
[[Category: | * Increased risk of cardiovascular disease | ||
[[Category: | * Liver toxicity | ||
[[Category: | * Suppression of natural testosterone production | ||
==Legal Status== | |||
The legal status of cloxotestosterone acetate varies by country. In many jurisdictions, it is classified as a controlled substance due to its potential for abuse and side effects. | |||
==Also see== | |||
* [[Anabolic steroid]] | |||
* [[Testosterone]] | |||
* [[Androgen replacement therapy]] | |||
* [[Steroid ester]] | |||
{{Anabolic steroids}} | |||
[[Category:Anabolic steroids]] | |||
[[Category:Androgens and anabolic steroids]] | |||
[[Category:Chloroarenes]] | |||
Latest revision as of 02:51, 11 December 2024
Cloxotestosterone Acetate
Cloxotestosterone acetate is a synthetic anabolic-androgenic steroid (AAS) and a derivative of testosterone. It is an ester of cloxotestosterone, which is a chlorinated form of testosterone. This compound was developed for potential use in androgen replacement therapy and other medical applications, but it is not widely used in clinical practice.
Chemical Structure and Properties[edit]
Cloxotestosterone acetate is characterized by the presence of a chlorine atom at the 4-position of the steroid nucleus and an acetate ester at the 17β-hydroxyl group. The chemical structure can be represented as follows:
- IUPAC name: (17β)-4-Chloroandrost-4-en-17-ol-3-one acetate
- Molecular formula: C21H29ClO3
- Molecular weight: 364.91 g/mol
The presence of the acetate ester increases the lipophilicity of the molecule, allowing for a slower release and prolonged duration of action when administered intramuscularly.
Pharmacology[edit]
Cloxotestosterone acetate acts as an agonist of the androgen receptor, similar to other anabolic steroids. It promotes protein synthesis and muscle growth, and it can also influence secondary sexual characteristics. The chlorination at the 4-position is intended to modify the activity and metabolism of the steroid, potentially reducing its androgenic effects while maintaining anabolic properties.
Medical Uses[edit]
Although cloxotestosterone acetate was developed for medical use, it is not commonly used in clinical practice. Potential applications include:
- Treatment of male hypogonadism
- Androgen replacement therapy
- Management of certain types of anemia
However, due to the availability of other more established and well-studied anabolic steroids, cloxotestosterone acetate is rarely prescribed.
Side Effects[edit]
As with other anabolic steroids, cloxotestosterone acetate can cause a range of side effects, particularly with long-term use or at high doses. These may include:
- Virilization in women
- Acne and oily skin
- Increased risk of cardiovascular disease
- Liver toxicity
- Suppression of natural testosterone production
Legal Status[edit]
The legal status of cloxotestosterone acetate varies by country. In many jurisdictions, it is classified as a controlled substance due to its potential for abuse and side effects.
Also see[edit]
