Starburst amacrine cell

Starburst amacrine cell
General Information
Latin
Greek
TA98
TA2
FMA
Details
System
Artery
Vein
Nerve
Lymphatic drainage
Precursor
Function
Identifiers
Clinical significance
Notes

The starburst amacrine cell is a type of amacrine cell found in the retina of the eye. These cells are crucial for the processing of visual information, particularly in the detection of motion and direction selectivity.

Structure

Starburst amacrine cells are characterized by their unique dendritic arborization, which resembles a starburst pattern. This distinctive structure allows them to interact with multiple bipolar cells and ganglion cells, facilitating complex synaptic connections.

Function

The primary function of starburst amacrine cells is to contribute to the direction selectivity of retinal ganglion cells. They release the neurotransmitters acetylcholine and GABA, which play a role in modulating the activity of neighboring cells. This modulation is essential for the detection of the direction of moving objects within the visual field.

Neurotransmitters

Starburst amacrine cells utilize two main neurotransmitters: acetylcholine and GABA. Acetylcholine is an excitatory neurotransmitter that enhances the response of ganglion cells, while GABA is inhibitory, providing a balance that is crucial for precise directional tuning.

Role in Vision

These cells are integral to the retina's ability to process motion. By influencing the ganglion cells, starburst amacrine cells help in the creation of a neural map of motion direction, which is then transmitted to the brain for further processing.

Research

Studies on starburst amacrine cells have provided insights into the mechanisms of direction selectivity and motion detection in the visual system. Research continues to explore their role in visual processing and potential implications for visual disorders.

See also

• Amacrine cell
• Retina
• Direction selectivity
• Visual system