External limiting membrane

  [[File:File:Gray881.png|frameless|alt=]]

Section of retina. (Membrana limitans externa labeled at right, third from the top.)

Details
Synonyms
Pronunciation
Carnegie stage
Days
Precursor
Gives rise to
Part of

The External limiting membrane (ELM) is a layer of the retina in the eye. It is not a true membrane, but a series of junctions that form a barrier within the retina.

Structure

The ELM is located towards the outer surface of the retina, between the inner nuclear layer and the outer plexiform layer. It is composed of a series of zonula adherens junctions between Müller cells and the photoreceptor cells.

Function

The ELM acts as a barrier and regulator between the neural retina and the retinal pigment epithelium. It plays a crucial role in maintaining the structural and functional integrity of the retina.

Clinical significance

Damage or disruption to the ELM can lead to various retinal diseases, including macular degeneration and retinitis pigmentosa.

See also

• Retina
• Retinal pigment epithelium
• Müller glia

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This code will create an article with an infobox at the top, including two images from Wikimedia Commons. The article is divided into sections for the structure, function, and clinical significance of the ELM, and includes internal links to related articles. The article is categorized under "Human eye anatomy" and "Retina".

• Photoreceptors: Rod and Cone cells
  Photoreceptors: Rod and Cone cells
• Diagram of the retina
  Diagram of the retina
• Structure of the retina
  Structure of the retina