Gemfibrozil

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Gemfibrozil

Gemfibrozil (/dʒɛmˈfaɪbroʊzɪl/) is a lipid-regulating medication used to decrease triglyceride levels in the body. It belongs to a class of drugs known as fibrates.

Etymology

The term "Gemfibrozil" is derived from its chemical name, 5-(2,5-dimethylphenoxy)-2,2-dimethylpentanoic acid. The prefix "Gem-" is derived from the word "geminal", referring to the two methyl groups attached to the same carbon atom in the molecule. The "-fibr-" part of the name refers to its classification as a fibrate drug.

Usage

Gemfibrozil is primarily used to treat hyperlipidemia, a condition characterized by abnormally elevated levels of lipids or lipoproteins in the blood. It is particularly effective in treating hypertriglyceridemia, a type of hyperlipidemia characterized by high levels of triglycerides.

Mechanism of Action

Gemfibrozil works by reducing the production of triglycerides in the liver, thereby lowering the overall levels of triglycerides and low-density lipoprotein (LDL) cholesterol in the blood. It also helps to increase the levels of high-density lipoprotein (HDL) cholesterol, which is beneficial for heart health.

Related Terms

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