Triparanol

From WikiMD.org
Jump to navigation Jump to search

Triparanol (pronounced: tri-par-a-nol) is a cholesterol lowering drug that was first introduced in the 1960s. It is also known by its trade name, Mer/29.

Etymology

The term "Triparanol" is derived from its chemical structure, which consists of three para positions on the benzene ring.

Pharmacology

Triparanol works by inhibiting the enzyme desmosterol reductase, which is involved in the final step of cholesterol synthesis. This results in a decrease in the levels of cholesterol in the body.

History

Triparanol was first introduced in the 1960s by the pharmaceutical company Merck & Co. However, it was withdrawn from the market in 1962 due to severe side effects, including cataracts, hair loss, and skin abnormalities.

Side Effects

The side effects of Triparanol include cataracts, hair loss, and skin abnormalities. These side effects were severe enough to lead to the withdrawal of the drug from the market.

Related Terms

External links

Esculaap.svg

This WikiMD dictionary article is a stub. You can help make it a full article.


Languages: - East Asian 中文, 日本, 한국어, South Asian हिन्दी, Urdu, বাংলা, తెలుగు, தமிழ், ಕನ್ನಡ,
Southeast Asian Indonesian, Vietnamese, Thai, မြန်မာဘာသာ, European español, Deutsch, français, русский, português do Brasil, Italian, polski