Muscle weakness

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Obesity, Sleep & Internal medicine
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Muscle weakness
Synonyms	Myasthenia
Pronounce	N/A
Specialty	Neurology, Physical medicine and rehabilitation
Symptoms	Weakness, fatigue, muscle atrophy
Complications	N/A
Onset	Can be sudden or gradual
Duration	Varies depending on cause
Types	N/A
Causes	Neurological disorders, muscle disorders, metabolic disorders, autoimmune diseases
Risks	Genetic predisposition, infections, medications
Diagnosis	Physical examination, electromyography, blood tests
Differential diagnosis	Muscle fatigue, paralysis, neuropathy
Prevention	N/A
Treatment	Depends on underlying cause; may include physical therapy, medications, surgery
Medication	N/A
Prognosis	Varies; some conditions are treatable, others may be progressive
Frequency	Common
Deaths	N/A

Muscle weakness, also known as myasthenia, represents a diminished ability of a muscle or group of muscles to generate force. This can be due to a myriad of causes ranging from general fatigue to more complex neurodegenerative diseases. The presentation of muscle weakness can vary significantly among individuals, depending on its etiology and affected muscle groups.

Definition

Muscle weakness describes a situation where the full strength or force that a muscle or a group of muscles would ordinarily exert is reduced. It can be localized to a specific area or be a generalized condition impacting the entire body.

Causes

Muscle weakness can be attributed to several factors and conditions:

• Neurological disorders: Such as ALS, MS, and Guillain-Barré syndrome.
• Muscular disorders: Including Muscular dystrophy and Myopathy.
• Metabolic conditions: Like diabetes or electrolyte imbalances.
• Nutritional deficiencies: Especially lack of Vitamin D or certain B vitamins.
• Infections: Some viral or bacterial infections can lead to transient muscle weakness.
• Medications: Certain drugs, like statins or corticosteroids, may cause muscle weakness as a side effect.
• Overexertion and lack of rest: Intense physical activity without adequate recovery can lead to temporary muscle fatigue and weakness.

Symptoms and Associated Conditions

Muscle weakness may present alongside other symptoms or conditions such as:

• Fatigue
• Atrophy (decrease in muscle mass)
• Twitches or spasms
• Cramps
• Pain or discomfort
• Decreased coordination
• Limited range of motion

Diagnosis

The process of diagnosing the cause of muscle weakness involves:

• Clinical Examination: Observing the patient's ability to perform certain tasks.
• EMG: A test that evaluates the electrical activity of muscles.
• Blood tests: To assess for underlying metabolic or nutritional issues.
• Imaging: MRI or CT scan might be used to visualize the affected muscle groups.
• Biopsy: In certain cases, a muscle biopsy might be taken to analyze the muscle tissue directly.

Treatment

The treatment of muscle weakness largely depends on its underlying cause:

• Physical therapy: To enhance muscle strength and flexibility.
• Medications: Like muscle relaxants, immune-modulating drugs, or specific treatments for underlying conditions.
• Nutritional supplements: To address any vitamin or mineral deficiencies.
• Rest and Rehabilitation: Particularly if the weakness is due to overexertion.

See Also

• Muscle
• Neuromuscular disease
• Muscle atrophy
• Physical rehabilitation

References

1. "Understanding Muscle Weakness." Journal of Clinical Neurophysiology.
2. "Diagnostic Approach to Muscle Weakness." Medical Clinical Reviews.
3. "Neurological Causes of Muscle Weakness." Neuromuscular Disorders.

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