Cerivastatin
Cerivastatin
Cerivastatin (pronounced: /ˌsɛrɪˈvæstətɪn/) is a synthetic lipid-lowering agent that was marketed by the pharmaceutical company Bayer under the trade name Baycol. It is a member of the statin class of hypolipidemics and was used to lower cholesterol.
Etymology
The term "Cerivastatin" is derived from the Latin cera meaning "wax" and vasta meaning "vast" or "great". The suffix "-statin" is common in drugs that inhibit the production of cholesterol.
Pharmacology
Cerivastatin works by inhibiting the enzyme HMG-CoA reductase, which plays a central role in the production of cholesterol in the liver. This results in decreased levels of LDL cholesterol, which is the main source of cholesterol buildup and blockage in the arteries.
Side Effects
The use of Cerivastatin has been associated with a higher incidence of rhabdomyolysis, a serious condition that can lead to kidney damage. This led to its withdrawal from the market in 2001.
Related Terms
External links
- Medical encyclopedia article on Cerivastatin
- Wikipedia's article - Cerivastatin
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